Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3642
Full metadata record
DC FieldValueLanguage
dc.contributor.authorUstun, Elvan-
dc.contributor.authorSahin, Neslihan-
dc.contributor.authorCelik, Cem-
dc.contributor.authorTutar, Ugur-
dc.contributor.authorOzdemir, Namik-
dc.contributor.authorGurbuz, Nevin-
dc.contributor.authorOzdemir, Ismail-
dc.date.accessioned2023-01-06T12:10:31Z-
dc.date.available2023-01-06T12:10:31Z-
dc.date.issued2021-
dc.identifier.citationUstun, E., Sahin, N., Celik, C., Tutar, U., Ozdemir, N., Gurbuz, N., Ozdemir, I. (2021). Synthesis, characterization, antimicrobial and antibiofilm activity, and molecular docking analysis of NHC precursors and their Ag-NHC complexes. Dalton Transactions, 50(42), 15400-15412.Doi:10.1039/d1dt02003jen_US
dc.identifier.isbn1477-9226-
dc.identifier.isbn1477-9234-
dc.identifier.urihttp://dx.doi.org/10.1039/d1dt02003j-
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000707138600001-
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/34647935-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3642-
dc.descriptionWoS Categories : Chemistry, Inorganic & Nuclear Web of Science Index : Science Citation Index Expanded (SCI-EXPANDED) Research Areas : Chemistryen_US
dc.description.abstractMicroorganisms attach to surfaces and interfaces and form biofilms which create a sheltered area for host cell response. Therefore, biofilms provide troubles in fields such as medicine, food, and pharmaceuticals. Inhibition of formation of biofilms through hindering of quorum sensing could be a method for the production of new generation antibiotics. In this study, four new benzimidazole type NHC precursors (1-allyl-3-benzyl-5,6-dimethylbenzimidazolium chloride, 1-allyl-3-(2,4,6-trimethylbenzyl)-5,6-dimethylbenzimidazolium chloride, 1-allyl-3-(2,3,5,6-tetramethylbenzyl)-5,6-dimethylbenzimidazolium chloride, and 1-allyl-3-(2,3,4,5,6-pentamethylbenzyl)-5,6-dimethylbenzimidazolium chloride and Ag-NHC complexes of these molecules were synthesized and characterized by elemental analysis, FT-IR spectroscopy, H-1, and C-13{H-1} NMR spectroscopy, LC-MS, and single crystal crystallography. Antimicrobial and biofilm formation inhibition activities of the molecules were evaluated. In addition, the activities of the molecules were examined in detail by molecular docking analysis. According to the results obtained, higher activity was achieved with the complex molecules when compared with the benzimidazole derivative ligands.en_US
dc.description.sponsorshipFunding Orgs : Scientific Research Projects Unit of Ondokuz Mays University [PYO.FEN.1906.19.001]; nonu University Research Fund [u-BAP:FBG-2021-2562] Funding Name Preferred : Scientific Research Projects Unit of Ondokuz Mays University(Ondokuz Mayis University); nonu University Research Fund Funding Text : This study was supported by the Scientific Research Projects Unit of Ondokuz Mays University (Project No: PYO.FEN.1906.19.001) and nonu University Research Fund (u-BAP:FBG-2021-2562).en_US
dc.language.isoengen_US
dc.publisherROYAL SOC CHEMISTRY CAMBRIDGEen_US
dc.relation.isversionof10.1039/d1dt02003jen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectN-HETEROCYCLIC CARBENE; BIOFILM FORMATION; STRUCTURAL-CHARACTERIZATION; CRYSTAL-STRUCTURES; ESCHERICHIA-COLI; SILVER(I); PROGRAMen_US
dc.titleSynthesis, characterization, antimicrobial and antibiofilm activity, and molecular docking analysis of NHC precursors and their Ag-NHC complexesen_US
dc.typearticleen_US
dc.relation.journalDALTON TRANSACTIONSen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0003-3371-9874en_US
dc.contributor.authorID0000-0001-6325-0216en_US
dc.contributor.authorID0000-0003-1498-4170en_US
dc.identifier.volume50en_US
dc.identifier.issue42en_US
dc.identifier.startpage15400en_US
dc.identifier.endpage15412en_US
Appears in Collections:Kimya

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.