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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Guler, Cigdem | - |
dc.contributor.author | Keskin, Gul | - |
dc.contributor.author | Yildirim, Sibel | - |
dc.date.accessioned | 2022-08-16T05:55:03Z | - |
dc.date.available | 2022-08-16T05:55:03Z | - |
dc.date.issued | 2020 | - |
dc.identifier.uri | http://doi.org/10.5152/eurjther.2020.19110 | - |
dc.identifier.uri | http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1654 | - |
dc.description.abstract | Objective: This study aimed to assess the efficacy of enamel matrix derivatives (EMD) used in combination with casein phosphopeptide amorphous calcium phosphate (CPP-ACP) to recover minerals to the enamel after artificial caries formation. Methods: Fifty enamel samples were prepared from the buccal surfaces of extracted human third molars. The samples were divided into five groups: (G1) Untreated enamel samples (control), (G2) Application of 500 ppm sodium fluoride (NaF), (G3) CPP-ACP, (G4) EMD, and (G5) CPP-ACP + EMD. All of the samples were placed in an acidic buffer solution for 96 hours to simulate a carious lesion. Ca/P ratios were calculated using energy dispersive X-ray spectroscopy (EDX). After seven days of the remineralization procedure, the mineral contents of the samples were re-measured. All the data were analyzed statistically. Results: There were no statistically significant differences in the mineral contents of the samples between the groups after demineralization (p>0.05). The Ca/P ratios of G2, G3, G4, and G5 increased significantly (p<0.05) after remineralization. The highest levels of the Ca/P ratio were obtained in G5. Conclusion: Despite the limitations of this in vitro study, the combined use of CPP-ACP and EMD may increase the remineralization potential. Furthermore, this procedures may be an alternative for providing enamel remineralization in future clinical trials. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | AVES, BUYUKDERE CAD 105-9, MECIDIYEKOY, SISLI, ISTANBUL 34394, TURKEY | en_US |
dc.relation.isversionof | 10.5152/eurjther.2020.19110 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Casein phosphopeptide amorphous calcium phosphate; enamel matrix derivatives; enamel remineralization; fluoride; SEM-EDX | en_US |
dc.subject | CPP-ACP; REMINERALIZATION; FLUORIDE; PEPTIDE | en_US |
dc.title | Is it Possible to Regain Lost Minerals to Initial Enamel Lesions Using Enamel Matrix Derivatives Combined with Casein Phosphopeptide Amorphous Calcium Phosphate: An in Vitro Study | en_US |
dc.type | article | en_US |
dc.relation.journal | EUROPEAN JOURNAL OF THERAPEUTICS | en_US |
dc.contributor.department | Ordu Üniversitesi | en_US |
dc.contributor.authorID | 0000-0002-2581-9050 | en_US |
dc.identifier.volume | 26 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 172 | en_US |
dc.identifier.endpage | 177 | en_US |
Appears in Collections: | Pedodonti |
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