Abstract:
Objective: The aim of the study is to determine the frequency of fragmented QRS (FQRS) in patients with SARS-COV-2.
Methods: A total of 125 consecutive patients over 20 years of age who were hospitalized for SARS-COV-2 between 20th March 2020 and 18th May 2020 were included in the study. The data of the patients in the inpatient ward and in the intensive care unit were recorded separately. The duration of QRS and presence of FQRS were evaluated by two experienced cardiologists. The patients were divided into two groups as FQRS positive and FQRS negative considering presence of FQRS. Moreover, the frequency of FQRS in the patients in the inpatient ward and in the intensive care unit were compared with each other.
Results: FQRS was found in 24% of the patients who had SARS-COV-2. There was no difference between FQRS positive and negative groups in terms of age and gender. Heart rate was higher in FQRS positive group. C-reactive protein (7.25 6.65 mg/dl vs. 4.80 4.48 mg/dl; p = .02) levels were also significantly higher in the FQRS positive group. In patients with SARS-COV-2, intensive care unit requirement increased with increasing levels of troponin (p b .000). A positive correlation was detected between serum CRP levels and FQRS (r = 0.204, p = .024).
Conclusions: The frequency of FQRS is high in patients with SARS-COV-2. Serum CRP levels increase with increasing frequency of FQRS in patients with SARS-COV-2 indicating that patients with FQRS are exposed to more inflammation. Presence of FQRS in SARS-COV-2 patients may be useful in predicting cardiovascular outcomes. (c) 2020 Elsevier Inc. All rights reserved.