DSpace Repository

Helicobacter Pylori Infection in Patients With Neurological Symptoms of Vitamin B12 Deficiency

Show simple item record

dc.contributor.author Ozcan, Tuba Aydemir
dc.contributor.author Aksoz, Kadir
dc.contributor.author Aksoy, Nazan
dc.contributor.author Noyan, Tevfik
dc.date.accessioned 2022-08-16T06:17:04Z
dc.date.available 2022-08-16T06:17:04Z
dc.date.issued 2013
dc.identifier.uri https://eds.p.ebscohost.com/eds/pdfviewer/pdfviewer?vid=0&sid=dc2e2227-b334-4d38-b4a3-46e23b8361fa%40redis
dc.identifier.uri http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1715
dc.description.abstract Background: Vitamin B12 is essential for DNA synthesis, formation of myelin sheaths, neurotransmitter synthesis, and erythropoiesis. Insufficient intake or disrupted absorption of vitamin B12 results in deficiency. Clinical manifestations of vitamin B12 deficiency include hematologic and neuropsychiatric disorders. Helicobacter pylori (H. pylori) is the most common chronic bacterial infection in humans. Some reports suggest that extraintestinal diseases are related to H. pylori infections. Some studies have shown strong associations between vitamin B12 and H. pylori infections. This study aims to investigate H. pylori infections in patients with neurological symptoms of vitamin B12 deficiency. Methods: The data of patients with Vitamin B12 deficiency who were admitted to neurology and gastroenterology outpatient clinics were scanned. The main inclusion criterion for the patients was having no other clinical conditions that account for the neurological symptoms. To evaluate the relationship with neurological symptoms, the patients were divided into two groups: Group I: H. pylori (+); and Group II: H. pylori (-). Results: Of the 40 patients included the study, H. plyori infection was seen in 27 (68%) patients. The most frequent neurological diseases were major depression + mild cognitive impairment (14.8%), and tension-type headache + major depression (25.9%) in patients with H. pylori infection. None of the patients showed hematological changes typical of megaloblastic anemia signs in CBC. Conclusions: We conclude that neuropsychiatric disorders due to Vitamin B12 deficiency may occur in the absence of anemia or an elevated MCV and it is frequently seen together with H. pylori infection. en_US
dc.language.iso eng en_US
dc.publisher JOURNAL NEUROLOGICAL SCIENCESEGE UNIV HOSP. FAC MED, DEPT NEUROSURGERY, BORNOVA-IZMIR TR35100, TURKEY en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Vitamin B12 deficiency, H.Pylori infection, neurological disorders en_US
dc.title Helicobacter Pylori Infection in Patients With Neurological Symptoms of Vitamin B12 Deficiency en_US
dc.type article en_US
dc.relation.journal JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH en_US
dc.contributor.department Ordu Üniversitesi en_US
dc.contributor.authorID 0000-0002-7733-0177 en_US
dc.identifier.volume 30 en_US
dc.identifier.issue 3 en_US
dc.identifier.startpage 487 en_US
dc.identifier.endpage 493 en_US


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account