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Laser Therapy Induces Increased Viability and Proliferation in Isolated Fibroblast Cells

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dc.contributor.author Belduz, Meral
dc.contributor.author Benkli, Yasin Atakan
dc.contributor.author Gokmenoglu, Ceren
dc.contributor.author Kara, Cankat
dc.contributor.author Kara, Nihal
dc.contributor.author Selamet, Hilal
dc.date.accessioned 2022-08-16T05:46:58Z
dc.date.available 2022-08-16T05:46:58Z
dc.date.issued 2020
dc.identifier.uri https://pubmed.ncbi.nlm.nih.gov/32163042/#:~:text=Results%3A%20In%20terms%20of%20the,and%202%20W%20application%20groups.&text=In%20addition%20to%20the%20proliferation,oral%20surgery%20and%20periodontal%20treatments.
dc.identifier.uri http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1621
dc.description.abstract Introduction. Laser therapy (LT), which stimulates natural biological processes in the application region, is frequently used in dental treatments. Objective. The aim of this study is to evaluate the effects of LT that could increase wound healing on fibroblast cells in vitro. Methods. Twenty-four hours after preparing the fibroblast cell culture plates, laser irradiation was performed 1, 2, and 3 times according to the test groups using an Nd:YAG (neodymium-doped yttrium aluminum garnet) laser with a power output of 0.5 W, 1 W, 2 W, and 3 W. Cell proliferation analysis was performed by MTT (methylthiazole diphenyl tetrazolium) assay at the twenty-fourth hour following the last laser application. Results. In terms of the laser irradiation power level, the most proliferation was observed in 1 W and 2 W application groups. Although a statistically significant increase was observed, particularly at 0.5 W, the increase at 1 W was greater than at a power output of 0.5 W. In terms of the number of laser irradiation applications, the most proliferation was observed in 2 and 3 application groups. The highest proliferation value was obtained with 1 W of power for 2 applications, and the lowest was with 3 W of power for 3 applications. Conclusions. The findings of this study show LT increased fibroblast cell proliferation, depending on the power output level of the laser and number of applications. In addition to the proliferation and mitotic activity of the fibroblast cells, the results demonstrate that LT could increase wound healing after oral surgery and periodontal treatments. en_US
dc.language.iso eng en_US
dc.publisher H M P COMMUNICATIONS, 83 GENERAL WARREN BLVD, STE 100, MALVERN, PA 19355 USA en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject laser therapy; Nd:YAG laser; fibroblast cells; wound healing; proliferation en_US
dc.subject RABBIT ORAL-MUCOSA; ANIMAL-MODEL; NDYAG LASER; YAG LASER; IRRADIATION; GINGIVAL; GROWTH; LIGHT; ND en_US
dc.title Laser Therapy Induces Increased Viability and Proliferation in Isolated Fibroblast Cells en_US
dc.type article en_US
dc.relation.journal WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE en_US
dc.contributor.department Ordu Üniversitesi en_US
dc.contributor.authorID 0000-0001-5356-3665 en_US
dc.contributor.authorID 0000-0002-0394-5961 en_US
dc.contributor.authorID 0000-0003-3681-6143 en_US
dc.identifier.volume 32 en_US
dc.identifier.issue 3 en_US
dc.identifier.startpage 69 en_US
dc.identifier.endpage 73 en_US


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