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http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3683
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DC Field | Value | Language |
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dc.contributor.author | Erturk, Aliye Gediz | - |
dc.contributor.author | Sahin, Arzu | - |
dc.contributor.author | Ay, Ebru Bati | - |
dc.contributor.author | Pelit, Emel | - |
dc.contributor.author | Bagdatli, Emine | - |
dc.contributor.author | Kulu, Irem | - |
dc.contributor.author | Gul, Melek | - |
dc.contributor.author | Mesci, Seda | - |
dc.contributor.author | Eryilmaz, Serpil | - |
dc.contributor.author | Ilter, Sirin Oba | - |
dc.contributor.author | Yildirim, Tuba | - |
dc.date.accessioned | 2023-01-06T12:18:53Z | - |
dc.date.available | 2023-01-06T12:18:53Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Erturk, AG., Sahin, A., Ay, EB., Pelit, E., Bagdatli, E., Kulu, I., Gul, M., Mesci, S., Eryilmaz, S., Ilter, SO., Yildirim, T. (2021). A Multidisciplinary Approach to Coronavirus Disease (COVID-19). Molecules, 26(12), -.Doi:10.3390/molecules26123526 | en_US |
dc.identifier.isbn | 1420-3049 | - |
dc.identifier.uri | http://dx.doi.org/10.3390/molecules26123526 | - |
dc.identifier.uri | https://www.webofscience.com/wos/woscc/full-record/WOS:000666658300001 | - |
dc.identifier.uri | https://pubmed.ncbi.nlm.nih.gov/34207756 | - |
dc.identifier.uri | http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3683 | - |
dc.description | WoS Categories : Biochemistry & Molecular Biology; Chemistry, Multidisciplinary Web of Science Index : Science Citation Index Expanded (SCI-EXPANDED) Research Areas : Biochemistry & Molecular Biology; Chemistry Open Access Designations : Green Published, gold | en_US |
dc.description.abstract | Since December 2019, humanity has faced an important global threat. Many studies have been published on the origin, structure, and mechanism of action of the SARS-CoV-2 virus and the treatment of its disease. The priority of scientists all over the world has been to direct their time to research this subject. In this review, we highlight chemical studies and therapeutic approaches to overcome COVID-19 with seven different sections. These sections are the structure and mechanism of action of SARS-CoV-2, immunotherapy and vaccine, computer-aided drug design, repurposing therapeutics for COVID-19, synthesis of new molecular structures against COVID-19, food safety/security and functional food components, and potential natural products against COVID-19. In this work, we aimed to screen all the newly synthesized compounds, repurposing chemicals covering antiviral, anti-inflammatory, antibacterial, antiparasitic, anticancer, antipsychotic, and antihistamine compounds against COVID-19. We also highlight computer-aided approaches to develop an anti-COVID-19 molecule. We explain that some phytochemicals and dietary supplements have been identified as antiviral bioproducts, which have almost been successfully tested against COVID-19. In addition, we present immunotherapy types, targets, immunotherapy and inflammation/mutations of the virus, immune response, and vaccine issues. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | MDPI BASEL | en_US |
dc.relation.isversionof | 10.3390/molecules26123526 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | DEPENDENT RNA-POLYMERASE; MOLECULAR DOCKING; IN-SILICO; CYTOKINE STORM; DOUBLE-BLIND; SONOCHEMICAL SYNTHESIS; POTENTIAL INHIBITORS; DRUG DESIGN; OPEN-LABEL; M-PRO | en_US |
dc.subject | SARS-CoV-2; COVID-19; cytokine storm; immunotherapy; vaccine development; in-silico research; small drugs; repurposing drugs; dietary supplements; natural products | en_US |
dc.title | A Multidisciplinary Approach to Coronavirus Disease (COVID-19) | en_US |
dc.type | article | en_US |
dc.relation.journal | MOLECULES | en_US |
dc.contributor.department | Ordu Üniversitesi | en_US |
dc.contributor.authorID | 0000-0002-0935-4644 | en_US |
dc.identifier.volume | 26 | en_US |
dc.identifier.issue | 12 | en_US |
Appears in Collections: | Kimya |
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