Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3683
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dc.contributor.authorErturk, Aliye Gediz-
dc.contributor.authorSahin, Arzu-
dc.contributor.authorAy, Ebru Bati-
dc.contributor.authorPelit, Emel-
dc.contributor.authorBagdatli, Emine-
dc.contributor.authorKulu, Irem-
dc.contributor.authorGul, Melek-
dc.contributor.authorMesci, Seda-
dc.contributor.authorEryilmaz, Serpil-
dc.contributor.authorIlter, Sirin Oba-
dc.contributor.authorYildirim, Tuba-
dc.date.accessioned2023-01-06T12:18:53Z-
dc.date.available2023-01-06T12:18:53Z-
dc.date.issued2021-
dc.identifier.citationErturk, AG., Sahin, A., Ay, EB., Pelit, E., Bagdatli, E., Kulu, I., Gul, M., Mesci, S., Eryilmaz, S., Ilter, SO., Yildirim, T. (2021). A Multidisciplinary Approach to Coronavirus Disease (COVID-19). Molecules, 26(12), -.Doi:10.3390/molecules26123526en_US
dc.identifier.isbn1420-3049-
dc.identifier.urihttp://dx.doi.org/10.3390/molecules26123526-
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000666658300001-
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/34207756-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3683-
dc.descriptionWoS Categories : Biochemistry & Molecular Biology; Chemistry, Multidisciplinary Web of Science Index : Science Citation Index Expanded (SCI-EXPANDED) Research Areas : Biochemistry & Molecular Biology; Chemistry Open Access Designations : Green Published, golden_US
dc.description.abstractSince December 2019, humanity has faced an important global threat. Many studies have been published on the origin, structure, and mechanism of action of the SARS-CoV-2 virus and the treatment of its disease. The priority of scientists all over the world has been to direct their time to research this subject. In this review, we highlight chemical studies and therapeutic approaches to overcome COVID-19 with seven different sections. These sections are the structure and mechanism of action of SARS-CoV-2, immunotherapy and vaccine, computer-aided drug design, repurposing therapeutics for COVID-19, synthesis of new molecular structures against COVID-19, food safety/security and functional food components, and potential natural products against COVID-19. In this work, we aimed to screen all the newly synthesized compounds, repurposing chemicals covering antiviral, anti-inflammatory, antibacterial, antiparasitic, anticancer, antipsychotic, and antihistamine compounds against COVID-19. We also highlight computer-aided approaches to develop an anti-COVID-19 molecule. We explain that some phytochemicals and dietary supplements have been identified as antiviral bioproducts, which have almost been successfully tested against COVID-19. In addition, we present immunotherapy types, targets, immunotherapy and inflammation/mutations of the virus, immune response, and vaccine issues.en_US
dc.language.isoengen_US
dc.publisherMDPI BASELen_US
dc.relation.isversionof10.3390/molecules26123526en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDEPENDENT RNA-POLYMERASE; MOLECULAR DOCKING; IN-SILICO; CYTOKINE STORM; DOUBLE-BLIND; SONOCHEMICAL SYNTHESIS; POTENTIAL INHIBITORS; DRUG DESIGN; OPEN-LABEL; M-PROen_US
dc.subjectSARS-CoV-2; COVID-19; cytokine storm; immunotherapy; vaccine development; in-silico research; small drugs; repurposing drugs; dietary supplements; natural productsen_US
dc.titleA Multidisciplinary Approach to Coronavirus Disease (COVID-19)en_US
dc.typearticleen_US
dc.relation.journalMOLECULESen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0002-0935-4644en_US
dc.identifier.volume26en_US
dc.identifier.issue12en_US
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