The Use of Neutrophil Lymphocyte Ratio in Patients Presenting to the Emergency Department with Chest Pain

Abstract

Objective: Objective: In this study, we aimed to determine the roles of neutrophil, MPV, and NLR, in the diagnosis of ACS and the differentiation of ACS subtypes (ST-elevation myocardial infarction and non-ST elevation myocardial infarction), in patients presented to the emergency department with chest pain and were diagnosed with ACS (acute coronary syndrome). Methods: This study was designed as a single-center, cross-sectional, and retrospective. 402 patients who were applied to University Hospital Emergency Department between January 2020 and November 2020; and registered to hospital automation system with chest pain; and underwent further examinations and treatments were included in the study. Ethical approval was obtained from the Local Clinical Research Ethics Committee before the study. Patients who were hospitalized after further examination, who received medical treatment, and did not undergo PCI (Percutaneous coronary intervention) were accepted as NSTMI (n = 202). Patients who were hospitalized after further examination and underwent PCI were accepted as STMI (n = 200). Results: 36.3% of the patients were female (n = 146) and 63.7% (n = 256) were male. The mean age of the cases was detected to be 61.46 +/- 14.06. The number of hospitalized ACS patients for NSTMI suspicion and received medical treatment was 202. The number of patients who underwent PCI and accepted as STMI was 200.Mean neutrophils, MPV, NLR, and Troponin values were also significantly higher than those who are not hospitalized (p <0.001). The mean WBC, Neutrophil, NLR, and Troponin values of the patients underwent PCI were also significantly higher than those without PCI (p <0.001). Conclusions: We believe that NLR is a diagnostic valuable that can be used as a biomarker in diagnosing ACS and determining the PCI.