Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3251
Title: The Effects of Pulsed Electromagnetic Field (PEMF) on Osteoblast-Like Cells Cultured on Titanium and Titanium-Zirconium Surfaces
Authors: Atalay, Belir
Aybar, Buket
Erguven, Mine
Emes, Yusuf
Bultan, Ozgur
Akca, Kivanc
Yalcin, Serhat
Baysal, Ugur
Issever, Halim
Cehreli, Murat Cavit
Bilir, Ayhan
Ordu Üniversitesi
0000-0003-3013-2533
0000-0002-6583-0684
Keywords: Implant surface PEMF titanium-zirconium alloy cell culture
Issue Date: 2013
Publisher: LIPPINCOTT WILLIAMS & WILKINSTWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103
Abstract: Background: Commercially pure Ti, together with Ti Ni, Ti-6Al-4V, and Ti-6Al-7Nb alloys, are among the materials currently being used for this purpose. Titanium-zirconium (TiZr) has been developed that allows SLActive surface modification and that has comparable or better mechanical strength and improved biocompatibility compared with existing Ti alloys. Furthermore, approaches have targeted making the implant surface more hydrophilic, as with the Straumann SLActive surface, a modification of the SLA surface. Purpose: The aim of this study is to evaluate the effects of pulsed electromagnetic field (PEMF) to the behavior of neonatal rat calvarial osteoblast-like cells cultured on commercially pure titanium (cpTi) and titanium-zirconium alloy (TiZr) discs with hydrophilic surface properties. Materials and Methods: Osteoblast cells were cultured on titanium and TiZr discs, and PEMF was applied. Cell proliferation rates, cell numbers, cell viability rates, alkaline phosphatase, and midkine (MK) levels were measured at 24 and 72 hours. Results: At 24 hours, the number of cells was significantly higher in the TiZr group. At 72 hours, TiZr had a significantly higher number of cells when compared to SLActive, SLActive + PEMF, and machine surface + PEMF groups. At 24 hours, cell proliferation was significantly higher in the TiZr group than SLActive and TiZr + PEMF group. At 72 hours, TiZr group had higher proliferation rate than machine surface and TiZr + PEMF. Cell proliferation in the machine surface group was lower than both SLActive + PEMF and machine surface + PEMF. MK levels of PEMF-treated groups were lower than untreated groups for 72 hours. Conclusions: Our findings conclude that TiZr surfaces are similar to cpTi surfaces in terms of biocompatibility. However, PEMF application has a higher stimulative effect on cells cultured on cpTi surfaces when compared to TiZr.
URI: http://doi.org/10.1097/SCS.0b013e31829a7ebc
http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3251
Appears in Collections:Protetik Diş Tedavisi

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