Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2591
Title: Comparing the Effects of Antiadhesive Materials after Abdominal Surgery
Authors: Cetin, Mehmet Fuat
Dogan, Sami
Erdem, Havva
Gunal, Omer
Ordu Üniversitesi
0000-0002-3074-0240
Keywords: Antiadhesive; Tension force; Adhesion; Abdominal surgery; olive oil
SMALL-BOWEL OBSTRUCTION; VITAMIN-E; ADHESIONS
Issue Date: 2020
Publisher: DUZCE UNIV, KONURALP YERLESKESI, DUZCE, 81620, TURKEY
Abstract: Objective: We aimed to evaluate and compare the effects of anti-adhesion materials, Seprafilm, Suprofilm, olive oil, and olive oil containing Vitamin E by measuring tension forces. Methods: 60 male Wistar-Albino rats were divided into six groups. The front side of the cecum and right abdominal parietal peritoneal wall were abrased. The rats were euthanized on the 14th postoperative day. Adhesions between intestines, omentum, other abdominal organs, cecum, incisionsites, and abdominal anterior wall peritoneum were all evaluated. Adhesion strength was measured with dynamometer. Histopathological evaluations of the adhesion area was performed. Results: Stage-I (0.43Newton) in Group-I, stage-IV (1.0540N) in Group-II, stage-II (0.6370N) in Group-III, stage-II in Group-IV (0, 5230N), stage-III (0.7620N) in Group-V, stage-IV (1.3560N) in Group-VI, were detected. A significant difference was found between these findings. P = 0.001, (p<0.05). Histopathological examination: It was found that GroupV-VI reduced inflammation, increased collagen production, fibroblastic activity and vascular proliferation. Conclusions: More objective evaluation can be made by measuring the tension force of the adhesions. Suprafilm can also be effectively used as an antiadhesive, such as Seprafilm. Olive oil and vitamin E require more studies to be used as antiadhesives.
URI: http://doi.org/10.18521/ktd.687794
http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2591
Appears in Collections:Cerrahi Tıp Bilimleri

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