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http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2509
Title: | Gold nanoparticle/polymer nanocomposite for highly sensitive drug-DNA interaction |
Authors: | Erdem, A. Kuralay, F. Ordu Üniversitesi 0000-0003-0356-9692 |
Keywords: | MITOMYCIN-CELECTROCHEMICAL BIOSENSORCARBON NANOTUBESPOLYMERGUANINESENSORPOLYVINYLFERROCENEGLUCOSEFILMVOLTAMMETRY |
Issue Date: | 2015 |
Publisher: | ROYAL SOC CHEMISTRYTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND |
Abstract: | The interaction of the anticancer drug mitomycin C (MC) and DNA immobilized on gold a nanoparticle/polyvinylferrocenium (AuNP/PVF+) coated electrode is presented. This is the first attempt to prepare a biocompatible nanoparticle/redox polymer composite in a one-step and easy electropolymerization procedure and then use the coated electrode for MC-DNA interaction. The prepared electrode exhibits high sensitivity for the investigation of drug-DNA interaction. |
URI: | http://doi.org/10.1039/c5an00061k http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2509 |
Appears in Collections: | Kimya |
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