Neutrophil-to-Lymphocyte Ratio Predicts Contrast-Induced Nephropathy in Patients Undergoing Primary Percutaneous Coronary Intervention

Abstract

Demirkol et al1 state that it would be better to use the modification of diet in renal disease (MDRD) in estimation of glomerular filtration rate in our study.2 There are reasons why we preferred the Cockcroft-Gault (CG) formula. First, MDRD and the chronic kidney disease epidemiology collaboration (CKD-EPI) equations require ethnic data adjustment.3 Second, the CKD-EPI equation gave more accurate estimated glomerular filtration rate value than the MDRD equation, especially in general population.4 Although, the CKD-EPI equation more accurately categorized individuals with respect to long-term clinical risk of incident end-stage renal disease, all-cause mortality, coronary heart disease, and stroke compared with the MDRD formula,5 in acute illness, such as acute myocardial infarction (MI), the results were different. Tomaszuk et al6 determined the correlation between renal function and 6-year mortality in patients with acute MI, treated successfully with primary percutaneous coronary intervention. They found that the CG formula is better than the MDRD and CKD-EPI equations in predicting mortality after acute MI.6 Our study involves patients with acute ST-segment elevated MI ; therefore, we preferred the CG formula. Also, another study reported that the MDRD equation provides better predictive value than the CKD-EPI equation on hospital adverse events among those with acute MI.7