Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2391
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dc.contributor.authorCankaya, Soner-
dc.contributor.authorCetinkol, Yeliz-
dc.contributor.authorEnginyurt, Ozgur-
dc.contributor.authorKorkmaz, Hakan-
dc.contributor.authorKorkmaz, Mukadder-
dc.contributor.authorYildirim, Arzu Altuncekic-
dc.date.accessioned2022-08-17T05:46:12Z-
dc.date.available2022-08-17T05:46:12Z-
dc.date.issued2016-
dc.identifier.urihttps://www.researchgate.net/publication/313327598_Nasopharyngeal_carriage_rates_of_streptococcus_pneumoniae_and_changes_after_conjugate_pneumococcal_vaccine-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2391-
dc.description.abstractBackground: Streptococcus pneumoniae infection in children usually begins with nasopharyngeal colonization that may be a significant risk factor for invasive pneumococcal disease. In this study it is aimed to determine the nasopharyngeal pneumococcal carriage rate in preschool-aged children, penicillin resistance rates of the isolated strains, risk factors for S. pneumoniae carriage. Materials and methods: Two hundred and fourteen children attending preschool were included in our study. The demographic characteristics and possible risk factors for pneumococcal carriage were investigated. Chi-square test and logistic regression model were used for statistical analysis. Results: Nasopharyngeal samples were taken from 214 healthy preschool children. No statistical difference was found between carrier and non-carriers with respect to age, gender, having respiratory tract infection within the last three months, presence of smokers in the family and number of people in the family. Thirty four of 214 children were unvaccinated against pneumococcus and 6 patients (17.6%) of these 34 children were found as S. pneumonia carrier. While 50% of pneumococcal isolates were susceptible to penicillin, the rate of high-level resistance to penicillin was 16.7% and intermediate level resistance rate was 33.3%. The pneumococcal carriage was found significantly increased in unvaccinated children compared to vaccinated children (P<0.0001). Conclusion: In our study the nasopharyngeal pneumococcal carriage rate was 2.8% in children aged between 4 and 6 years. This rate is lower than the data previously reported. Carriage was not seen in vaccinated children in our study. We think that routine pneumococcal vaccination is the major factor underlying this decrease. These results should be supported with multicenter studies.en_US
dc.language.isoengen_US
dc.publisherALLIED ACAD, 40 BLOOMSBURY WAY, LOWER GROUND FLR, LONDON, WC1A 2SE, ENGLANDen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectANTIMICROBIAL RESISTANCE; SEROTYPE DISTRIBUTION; HEALTHY-CHILDREN; ANTIBIOTIC SUSCEPTIBILITY; COLONIZATION; MULTICENTER; PREVALENCEen_US
dc.subjectPneumococcal infections; Streptococcal infections; Vaccinationen_US
dc.titleNasopharyngeal carriage rates of streptococcus pneumoniae and changes after conjugate pneumococcal vaccine.en_US
dc.typearticleen_US
dc.relation.journalBIOMEDICAL RESEARCH-INDIAen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0001-8056-1892en_US
dc.contributor.authorID0000-0002-0988-4354en_US
dc.contributor.authorID0000-0002-5966-9126en_US
dc.contributor.authorID0000-0003-1141-9838en_US
dc.contributor.authorID0000-0003-4271-3140en_US
dc.contributor.authorID0000-0003-4940-4498en_US
dc.identifier.volume27en_US
dc.identifier.issue1en_US
dc.identifier.startpage172en_US
dc.identifier.endpage176en_US
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