Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2320
Title: Serum levels of nesfatin-1 and irisin in obese children
Authors: Dokumacioglu, Eda
Erturk, Emine Yurdakul
Iskender, Hatice
Kaynar, Ozgur
Sahin, Arzu
Ordu Üniversitesi
0000-0001-5366-647X
Keywords: Irisin; nesfatin-1; obesity; oxidative stress
OXIDATIVE STRESS; CHILDHOOD OBESITY; CIRCULATING LEVELS; INFLAMMATION; ACID; INSULIN; ASSAY; RISK
Issue Date: 2020
Publisher: JOHN LIBBEY EUROTEXT LTD, 30, RUE BERTHOLLET, BATIMENT A, 94110 ARCUEIL, FRANCE
Abstract: Background:Along with the developing technology in the modern age, physical activity had decreased considerably in children and adolescents alike with a concomittant and rapid increase in the prevalence of childhood obsesity. The purpose of the present study is to measure the levels of serum nesfatin-1 and irisin in obese children.Methods:The present study was carried out with a total of 62 children, including 32 obese children diagnosed between June 2017 and October 2017 and 30 healthy children. Serum nesfatin-1, irisin, SOD,MDA, fasting blood glucose, total cholesterol (TC), triglyceride (TG), HDL-C, LDL-C, aspartate amino transferase (AST), alanine amino transferase (ALT)), blood urea nitrogen (BUN), C-reactive protein (CRP), calcium (Ca), sodium (Na), potassium (P), chromium (Cr), ferritin, and vitamin B(12)data were collected for each patient.Results:In our study, mean nesfatin-1 and SOD values of the obesity group were lower than those of the control group (p <0.05, p <0.001), whereas irisin and MDA values were higher than those of the control group (p <0.001).Conclusion:Childhood obesity is still a significant global problem, despite increased social awareness and numerous preventive healthcare interventions. We believe that all the prospective studies to be carried out to evaluate the relationship between obesity-irisin-nesfatin-1 triad, will make positive contributions to treatment of obesity.
URI: https://link.springer.com/article/10.1684/ecn.2020.0444
http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2320
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