Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2252
Title: Amebicidal effects of fenugreek (Trigonella foenum-graecum) against Acanthamoeba cysts
Authors: Arici, Yeliz Kasko
Baldemir, Ayse
Ildiz, Nilay
Kacmaz, Gamze
Karaman, Ulku
Kaya, Yasemin
Koloren, Zeynep
Konca, Yusuf
Ordu Üniversitesi
0000-0001-6820-0381
0000-0001-7360-8090
Keywords: Acanthamoeba castellanii; amebicidal effect; fenugreek; Trigonella foenum-graecum
Issue Date: 2019
Publisher: WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
Abstract: Trigonella foenum-graecum L. (TF) is known to the public as a chest emollient, mucous expectorant, laxative and is used to prevent maturation of boils and diabetes since ancient times. In this study, we aimed to determine the amebicidal effects against Acanthamoeba cysts. Plant extracts were prepared at concentrations of 1, 2, 4, 8, 16, and 32 mg/ml and were placed in a hemocytometer with cell counts 22 x 10(6) cell/ml. The fatty acid profiles of TF seeds were determined. Standard Acanthamoeba cysts were added and incubated at 25 degrees C. The viability of the parasite was checked and recorded at hours 3, 24, 48, 72, 96, and 102. The values of lethal concentration doses (LD50 and LD90) were calculated using probit analysis. This study revealed that T. foenum-graecum prevented proliferation of the parasite at certain times. However, further for in vivo and controlled experimental studies are needed in order to find out how to use this plant as medication.
URI: http://doi.org/10.1002/fsn3.849
http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2252
Appears in Collections:Dahili Tıp Bilimleri

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