Triphasic mitral flow pattern may indicate subclinical left ventricular systolic dysfunction

Abstract

Purpose In this study, the presence and severity of left ventricular (LV) systolic dysfunction were investigated by speckle tracking echocardiography (STE) technique in patients with mitral triphasic mitral flow pattern (TMFP). The aim of the study was to evaluate the possible role of TMFP in the ethiopathogenesis of congestive heart failure. Methods and results A total of 45 patients who were diagnosed with TMFP and 30 age- and gender-matched healthy volunteers were included in the study. The mean age in the study and control groups was 64 +/- 12 and 62 +/- 11 (P = .642), respectively. When echocardiographic parameters were evaluated, LV ejection fraction was found to be 63% +/- 14 and 64 +/- 12 (P = .745), in the study and control groups, respectively. LV end-diastolic and systolic diameters and LV mass index were also similar (P < .05). When LV diastolic parameters were compared, diastolic dysfunction was detected in 38 (84.4%) patients in the study population and 13 patients (43.3%) in the control group (P < .001). When STE findings were evaluated, both global longitidunal strain and global circumferential strain were significantly lower in the TMFP group when compared to controls (18.3 +/- 1.7 vs 21.5 +/- 1.5, P < .001 and 17.9 +/- 1.6 vs 21.3 +/- 2.1, P < .001, respectively). Conclusion TMFP results in LV systolic dysfunction. Therefore, these patients may develop congestive heart failure in the long term. It will be rational that the patients with TMFP should be followed up more closely in terms of preventing manifest heart failure symptoms.