Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1941
Title: Diagnostic Value of Cyclophilin A in Acute Ischemic Stroke
Authors: Aksut, Nurhak
Altay, Diler Us
Beslioglu, Necla
Eryigit, Umut
Karaca, Yunus
Karatas, Mevlut
Mentese, Ahmet
Orem, Asim
Sahin, Aynur
Tatli, Ozgur
Ordu Üniversitesi
0000-0002-0465-8403
0000-0003-0263-7630
Keywords: Acute ischemic stroke; cyclophilin A; emergency department
SMOOTH-MUSCLE-CELLS; OXIDATIVE STRESS; DISEASE
Issue Date: 2017
Publisher: AVES, BUYUKDERE CAD 105-9, MECIDIYEKOY, SISLI, ISTANBUL 34394, TURKEY
Abstract: Aim: The early diagnosis and treatment of patients presenting to the emergency department symptoms of stroke can significantly reduce mortality and morbidity rates associated with it. This study aimed to investigate the diagnostic value of serum yclophilin A levels in our study group who presented to the emergency department with symptoms of acute ischemic stroke. Materials and Methods: In total, 114 patients diagnosed with acute ischemic stroke between October 2013 and October 2014 and a control group of 66 healthy volunteers were included. Cyclophilin A levels in the patient and control groups were compared. Results: The median cyclophilin A levels in the patient and control groups measured at the time of presentation were 13.47 (11.97-17.92) ng/mL and 11.54 (8.48-16.22) ng/mL, respectively. These levels were significantly higher in the patient group than in the control group (p<0.05). Conclusion: Plasma cyclophilin A levels were significantly higher in the patient group than in the control group.
URI: http://doi.org/10.5152/eajem.2017.35119
https://www.researchgate.net/publication/317317605_Diagnostic_Value_of_Cyclophilin_A_in_Acute_Ischemic_Stroke
http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1941
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