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http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/190Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | Prof. Dr. Kelebekli, Latif | - |
| dc.contributor.author | Yılmaz, Fatma Zehra | - |
| dc.date.accessioned | 2022-08-10T10:41:07Z | - |
| dc.date.available | 2022-08-10T10:41:07Z | - |
| dc.date.issued | 2019 | - |
| dc.date.submitted | 2019 | - |
| dc.identifier.uri | http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/190 | - |
| dc.description.abstract | Bu çalışma, benzokonduritollerin stereospesifik sentezini kapsamaktadır. Okzobenzonorbornadien anahtar bileşiği antranilik asit’den çıkarak elde edildi. Okzobenzonorbornadien, OsO4 katalizörlüğünde N-metil morfolin oksit (NMO) ile reaksiyonun ardından, asetik anhidrit (Ac2O) ile asetillenerek karşılık gelen diasetat bileşiği stereokontrollü olarak elde edildi. Diasetat bileşiğinin asit katalizörlüğünde Ac2O ile reaksiyonu benzokonduritol tetraasetatları verdi. Eldeki tetraasetatların bazik şartlarda metanol içerisinde amonyak (NH3) ile reaksiyonu sonucu benzokonduritol C ve benzokonduritol D yüksek verimle sentezlendi. Tüm bileşiklerin yapısı spektroskopik yöntemlerle (NMR, IR ve kütle) aydınlatıldı., | en_US |
| dc.description.abstract | Bu çalışma, benzokonduritollerin stereospesifik sentezini kapsamaktadır. Okzobenzonorbornadien anahtar biThis study comprises the stereospecific synthesis of benzochonduritols. The oxobenzonorbornadiene that is key compound was obtained starting from anthranilic acid. The double bond in the oxobenzonorbornadiene was oxidized with OsO4/ NMO (N-methyl morpholine oxide) followed by acetylation with Ac2O gave the diacetate compound as stereocontrolled. The reaction of the diacetate compound with acid-catalyzed Ac2O led to benzochonduritol tetraacetates. Benzochonduritol C and benzochonduritol D in high yields were synthesized by hydrolysis of tetraacetates with NH3 in methanol under basic conditions The structures of the whole compounds were elucidated by spectroscopic methods (NMR, IR, and mass).leşiği antranilik asit’den çıkarak elde edildi. Okzobenzonorbornadien, OsO4 katalizörlüğünde N-metil morfolin oksit (NMO) ile reaksiyonun ardından, asetik anhidrit (Ac2O) ile asetillenerek karşılık gelen diasetat bileşiği stereokontrollü olarak elde edildi. Diasetat bileşiğinin asit katalizörlüğünde Ac2O ile reaksiyonu benzokonduritol tetraasetatları verdi. Eldeki tetraasetatların bazik şartlarda metanol içerisinde amonyak (NH3) ile reaksiyonu sonucu benzokonduritol C ve benzokonduritol D yüksek verimle sentezlendi. Tüm bileşiklerin yapısı spektroskopik yöntemlerle (NMR, IR ve kütle) aydınlatıldı.,This study comprises the stereospecific synthesis of benzochonduritols. The oxobenzonorbornadiene that is key compound was obtained starting from anthranilic acid. The double bond in the oxobenzonorbornadiene was oxidized with OsO4/ NMO (N-methyl morpholine oxide) followed by acetylation with Ac2O gave the diacetate compound as stereocontrolled. The reaction of the diacetate compound with acid-catalyzed Ac2O led to benzochonduritol tetraacetates. Benzochonduritol C and benzochonduritol D in high yields were synthesized by hydrolysis of tetraacetates with NH3 in methanol under basic conditions The structures of the whole compounds were elucidated by spectroscopic methods (NMR, IR, and mass). | en_US |
| dc.language.iso | tur | en_US |
| dc.publisher | Fen Bilimleri Enstitüsü | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Benzokonduritol, konduritoller, aromatik tetroller, asit katalizli reaksiyonlar, tetroller | en_US |
| dc.subject | Benzoconduritol, conduritols, aromatic tetrols, acid-catalyzed reactions, tetrols | en_US |
| dc.title | BENZOKONDURİTOLLERİN STEREOSPEİFİK SENTEZİ | en_US |
| dc.title.alternative | This study comprises the stereospecific synthesis of benzochonduritols. The oxobenzonorbornadiene that is key compound was obtained starting from anthranilic acid. The double bond in the oxobenzonorbornadiene was oxidized with OsO4/ NMO (N-methyl morpholine oxide) followed by acetylation with Ac2O gave the diacetate compound as stereocontrolled. The reaction of the diacetate compound with acidcatalyzed Ac2O led to benzochonduritol tetraacetates. Benzochonduritol C and benzochonduritol D in high yields were synthesized by hydrolysis of tetraacetates with NH3 in methanol under basic conditions The structures of the whole compounds were elucidated by spectroscopic methods (NMR, IR, and mass). | en_US |
| dc.type | masterThesis | en_US |
| dc.contributor.department | Ordu Üniversitesi | en_US |
| dc.contributor.department | Fen Bilimleri Enstitüsü | en_US |
| Appears in Collections: | Fen Bilimleri Enstitüsü | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 10310643.pdf | 10310643 | 2.73 MB | Adobe PDF |  View/Open |
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