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Acetylcholinesterase inhibitory and antioxidant properties of Cyclotrichium niveum, Thymus praecox subsp caucasicus var. caucasicus, Echinacea purpurea and E. pallida

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dc.contributor.author Orhan, I.
dc.contributor.author Senol, F. S.
dc.contributor.author Guelpinar, A. R.
dc.contributor.author Kartal, M.
dc.contributor.author Sekeroglu, N.
dc.contributor.author Deveci, M.
dc.contributor.author Kan, Y.
dc.contributor.author Sener, B.
dc.date.accessioned 2024-03-26T07:00:13Z
dc.date.available 2024-03-26T07:00:13Z
dc.date.issued 2009
dc.identifier.citation Orhan, I., Senol, FS., Gülpinar, AR., Kartal, M., Sekeroglu, N., Deveci, M., Kan, Y., Sener, B. (2009). Acetylcholinesterase inhibitory and antioxidant properties of Cyclotrichium niveum, Thymus praecox subsp caucasicus var. caucasicus, Echinacea purpurea and E. pallida. Food Chem. Toxicol., 47(6), 1304-1310. https://doi.org/10.1016/j.fct.2009.03.004 en_US
dc.identifier.issn 0278-6915
dc.identifier.issn 1873-6351
dc.identifier.uri http://dx.doi.org/10.1016/j.fct.2009.03.004
dc.identifier.uri https://www.webofscience.com/wos/woscc/full-record/WOS:000266418300037
dc.identifier.uri http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/5280
dc.description WoS Categories: Food Science & Technology; Toxicology en_US
dc.description Web of Science Index: Science Citation Index Expanded (SCI-EXPANDED) en_US
dc.description Research Areas: Food Science & Technology; Toxicology en_US
dc.description.abstract The dichloromethane, ethyl acetate, ethanol, and aqueous extracts of Cyclotrichium niveum (CN) and Thymus praecox subsp. caucasicus var. caucasicus (TP), Echinacea purpurea (EPU), and E pallida (EPA) along with the essential oils of CN and TP were assessed for their anti-acetylcholinesterase (AChE) and antioxidant activities. AChE inhibition was estimated using spectrophotometric method of Ellman. Antioxidant activity was evaluated by 2,2-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging and ferrous ion-chelating power tests. Ferric-reducing antioxidant power (FRAP) of CN and TP were also tested. CN essential oil was found to contain isomenthone (56.21%) and pulegone (19.76%). The ethyl acetate (83.11-87.98%) and dichloromethane (73.45-84.02%) extracts of CN showed the highest AChE inhibition. The ethyl acetate and ethanol extracts of TP exerted significant DPPH scavenger effect. The water extracts of CN and TP and the chloroform extract of the aerial parts of EPU displayed the highest ferrous ion-chelating effect. The leaf and flower essential oils of TP had the best FRAP. (C) 2009 Elsevier Ltd. All rights reserved. en_US
dc.description.sponsorship Turkish Scientific and Technical Research Council (TUBITAK) en_US
dc.language.iso eng en_US
dc.publisher PERGAMON-ELSEVIER SCIENCE LTD-OXFORD en_US
dc.relation.isversionof 10.1016/j.fct.2009.03.004 en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Cyclotrichium niveum, Thymus praecox subsp caucasicus var. caucasicus, Echinacea, Essential oil, Acetylcholinesterase inhibition, Antioxidant activity en_US
dc.subject ESSENTIAL OILS, CHEMICAL-COMPOSITION, ANTICHOLINESTERASE, EXTRACTS, SALVIA, DERIVATIVES en_US
dc.title Acetylcholinesterase inhibitory and antioxidant properties of Cyclotrichium niveum, Thymus praecox subsp caucasicus var. caucasicus, Echinacea purpurea and E. pallida en_US
dc.type article en_US
dc.relation.journal FOOD AND CHEMICAL TOXICOLOGY en_US
dc.contributor.department Ordu Üniversitesi en_US
dc.contributor.authorID 0000-0002-5850-9841 en_US
dc.contributor.authorID 0000-0002-7379-5436 en_US
dc.contributor.authorID 0000-0003-3538-2769 en_US
dc.identifier.volume 47 en_US
dc.identifier.issue 6 en_US
dc.identifier.startpage 1304 en_US
dc.identifier.endpage 1310 en_US


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