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Modified model for end-stage liver disease score predicts 30-day mortality in high-risk patients with acute pulmonary embolism admitted to intensive care units

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dc.contributor.author Idin, Kadir
dc.contributor.author Dereli, Seckin
dc.contributor.author Kaya, Ahmet
dc.contributor.author Yenercag, Mustafa
dc.contributor.author Yilmaz, Ahmet Seyda
dc.contributor.author Tayfur, Kaptaniderya
dc.contributor.author Gulcu, Oktay
dc.date.accessioned 2023-01-06T12:16:36Z
dc.date.available 2023-01-06T12:16:36Z
dc.date.issued 2021
dc.identifier.citation Idin, K., Dereli, S., Kaya, A., Yenercag, M., Yilmaz, AS., Tayfur, K., Gulcu, O. (2021). Modified model for end-stage liver disease score predicts 30-day mortality in high-risk patients with acute pulmonary embolism admitted to intensive care units. Scandinavian Cardiovascular Journal, 55(4), 237-244.Doi:10.1080/14017431.2021.1876912 en_US
dc.identifier.isbn 1401-7431
dc.identifier.isbn 1651-2006
dc.identifier.uri http://dx.doi.org/10.1080/14017431.2021.1876912
dc.identifier.uri https://www.webofscience.com/wos/woscc/full-record/WOS:000611631100001
dc.identifier.uri https://pubmed.ncbi.nlm.nih.gov/33491501
dc.identifier.uri http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3672
dc.description WoS Categories : Cardiac & Cardiovascular Systems Web of Science Index : Science Citation Index Expanded (SCI-EXPANDED) Research Areas : Cardiovascular System & Cardiology Open Access Designations : Bronze en_US
dc.description.abstract Objectives The Model for End-stage Liver Disease excluding the international normalised ratio that is derived from prothrombin time which is calculated as a ratio of the patient's prothrombin time to a control prothrombin time standardized (MELD-XI) and modified MELD, which uses albumin in place of the international normalised ratio (MELD-Albumin) scores reflect liver and renal function and are predictors of mortality. However, their prognostic value in acute pulmonary embolism (APE) has not been studied. Design We assessed the predictive value of the MELD scores in patients diagnosed with high-risk APE admitted to the intensive care unit. The primary outcome was 30-day mortality. Results Of the 273 patients included in the study, 231 were survivors and 42 were non-survivors. The mortality rate was 15.3%. The mean MELD-XI and MELD-Albumin scores were significantly higher in the non-survivors than in the survivors (MELD XI, 11.8 +/- 1.8 and 10.6 +/- 1.43, respectively; p = .002; MELD-Albumin, 10.5 +/- 1.6 and 8.7 +/- 1.1, respectively; p = .001). The multiple logistic regression analysis identified the MELD-XI (hazard ratio: 3.029, confidence interval: 1.06-1.21, p = .007) and MELD-Albumin (hazard ratio: 1.13, confidence interval: 1.06-1.21, p = .002) scores as independent predictors of mortality. Receiver operating characteristic analysis revealed that the predictive power of the MELD-Albumin score (0.871 +/- 0.014; p < .001) was higher than those of the MELD-XI (0.726 +/- 0.022, p < .001), APACHE III (0.682 +/- 0.024, p < .001), and PESI (0.624 +/- 0.023, p < .001) scores. Conclusions The MELD-Albumin score is an easily calculable, reliable, and practical risk assessment tool and independent predictor of 30-day mortality in patients with high-risk APE. en_US
dc.language.iso eng en_US
dc.publisher TAYLOR & FRANCIS LTD ABINGDON en_US
dc.relation.isversionof 10.1080/14017431.2021.1876912 en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Acute pulmonary embolism; MELD-XI score; MELD-Albumin score; mortality; intensive care unit en_US
dc.title Modified model for end-stage liver disease score predicts 30-day mortality in high-risk patients with acute pulmonary embolism admitted to intensive care units en_US
dc.type article en_US
dc.relation.journal SCANDINAVIAN CARDIOVASCULAR JOURNAL en_US
dc.contributor.department Ordu Üniversitesi en_US
dc.contributor.authorID 0000-0003-0090-3835 en_US
dc.contributor.authorID 0000-0002-0933-7852 en_US
dc.contributor.authorID 0000-0003-3864-4023 en_US
dc.identifier.volume 55 en_US
dc.identifier.issue 4 en_US
dc.identifier.startpage 237 en_US
dc.identifier.endpage 244 en_US


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