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Haemodynamic Responses to Tracheal Intubation Using Propofol, Etomidate and Etomidate-Propofol Combination in Anaesthesia Induction

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dc.contributor.author Hanci, Volkan
dc.contributor.author Kucuk, Ahmet
dc.contributor.author Tas, Nilay
dc.contributor.author Yagan, Ozgur
dc.contributor.author Yurtlu, Bulent Serhan
dc.date.accessioned 2022-08-17T07:02:13Z
dc.date.available 2022-08-17T07:02:13Z
dc.date.issued 2015
dc.identifier.uri http://doi.org/10.15171/jcvtr.2015.30
dc.identifier.uri http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2660
dc.description.abstract Introduction: The aim of this study was to measure the haemodynamic responses to a etomidate-propofol combination used for anaesthesia induction and to compare the haemodynamic responses with the separate use of each drug. Methods: The patients were randomly divided into three groups as group P (n = 30, propofol 2.5 mg kg(-1)), group E (n = 30, etomidate 0.3 mg kg(-1)) and group PE (n = 30, propofol 1.25 mg kg(-1) + etomidate 0.15 mg kg(-1)). For each patient, the times of measurement of the heart rate (HR) and mean arterial pressure values were defined as baseline, after the induction, before the intubation, immediately after the intubation and 1, 2, 3, 4, 5 and 10 minutes after the intubation. Results: In all 3 groups, a significant decrease in MAP values were seen at T2 and T3 compared to the baseline values, and this decrease was greater in group P compared to that in group E and PE (P < 0.001, P < 0.01). A significant increase was seen in all 3 groups in the mean arterial pressure (MAP) value at T4 after the intubation. When the groups were compared with each other, this increase was greater in group E than in the other two groups (with group P, P < 0.001; with group PE, P < 0.01). Conclusion: Etomidate-propofol combination may be a valuable alternative when extremes of hypotensive and hypertensive responses due to propofol and etomidate are best to be avoided. en_US
dc.language.iso eng en_US
dc.publisher TABRIZ UNIV MEDICAL SCIENCES & HEALTH SERVICESDANESHGHAH ST, TABRIZ, REPUBLIC ISLAMIC 51664-14766, IRAN en_US
dc.relation.isversionof 10.15171/jcvtr.2015.30 en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject MYOCARDIAL-INFARCTIONGENERAL-ANESTHESIAINJECTION PAINFENTANYLMIDAZOLAMCOINDUCTIONPREDICTORSREDUCTIONMYOCLONUSLIDOCAINE en_US
dc.subject PropofolEtomidateEndotracheal IntubationHemodynamic en_US
dc.title Haemodynamic Responses to Tracheal Intubation Using Propofol, Etomidate and Etomidate-Propofol Combination in Anaesthesia Induction en_US
dc.type article en_US
dc.relation.journal JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH en_US
dc.contributor.department Ordu Üniversitesi en_US
dc.contributor.authorID 0000-0002-2227-194X en_US
dc.contributor.authorID 0000-0003-0472-2206 en_US
dc.contributor.authorID 0000-0003-1596-1421 en_US
dc.contributor.authorID 0000-0003-3020-1586 en_US
dc.identifier.volume 7 en_US
dc.identifier.issue 4 en_US
dc.identifier.startpage 134 en_US
dc.identifier.endpage 140 en_US


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