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Context Sensitive Links 1 of 1 Evaluation of the Association of Sleep Apnea-Related Systemic Inflammation with CRP, ESR, and Neutrophil-to-Lymphocyte Ratio

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dc.contributor.author Ayyildiz, Sema Nur
dc.contributor.author Cankaya, Soner
dc.contributor.author Korkmaz, Hakan
dc.contributor.author Korkmaz, Mukadder
dc.contributor.author Kucuker, Fatma
dc.date.accessioned 2022-08-17T07:00:31Z
dc.date.available 2022-08-17T07:00:31Z
dc.date.issued 2015
dc.identifier.uri http://doi.org/10.12659/MSM.893175
dc.identifier.uri http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2651
dc.description.abstract Background: Obstructive sleep apnea syndrome (OSAS) is characterized by cyclic episodes of hypoxemia and reoxygenation. It has been suggested that OSAS is associated with chronic inflammation within the microvasculature. This low-grade inflammation may play a role in the pathophysiology of OSAS-related comorbidities. Evaluation of the inflammatory markers may predict the degree of the systemic inflammation and this may be a prognostic factor for future adverse events such as cardiovascular risks. Proinflammatory cytokines have been extensively studied in sleep-disordered breathing. Neutrophil-to-lymphocyte ratio is a recently described indicator of systemic inflammation, but it has not been studied in OSAS patients. In this study we aimed to evaluate the easily measurable parameters of systemic inflammation in these patients. We conducted this study to examine the association among OSAS and C-reactive protein, erythrocyte sedimentation rate, and neutrophil-to-lymphocyte ratio. Material/Methods: OSAS patients who underwent overnight polysomnography were studied retrospectively. They were divided into 4 groups: control, mild, moderate, and severe OSAS patients. Blood test results and inflammatory markers were compared between the groups. One-way ANOVA and Kruskall-Wallis H test were used for statistical analysis. Results: A total of 147 patients were included in the study. No differences in evaluated inflammatory markers were observed among the 4 groups. Conclusions: Evaluation of the OSAS-related systemic inflammation is not likely to be possible by CRP, ESR, or neutrophil-to-lymphocyte ratio measurements. These markers do not seem to be associated with the degree of the upper airway obstruction. en_US
dc.language.iso eng en_US
dc.publisher INT SCIENTIFIC INFORMATION, INC150 BROADHOLLOW RD, STE 114, MELVILLE, NY 11747 en_US
dc.relation.isversionof 10.12659/MSM.893175 en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject C-REACTIVE PROTEINPROGNOSTIC-FACTORPRETREATMENT NEUTROPHILCONSEQUENCESELEVATIONRISKRESTRICTIONDURATIONTHERAPYMARKERS en_US
dc.subject LymphocytesNeutrophilsSleep Apnea,ObstructiveSystemic Inflammatory Response Syndrome en_US
dc.title Context Sensitive Links 1 of 1 Evaluation of the Association of Sleep Apnea-Related Systemic Inflammation with CRP, ESR, and Neutrophil-to-Lymphocyte Ratio en_US
dc.type article en_US
dc.relation.journal MEDICAL SCIENCE MONITOR en_US
dc.contributor.department Ordu Üniversitesi en_US
dc.contributor.authorID 0000-0001-8056-1892 en_US
dc.contributor.authorID 0000-0002-0988-4354 en_US
dc.contributor.authorID 0000-0003-4271-3140 en_US
dc.identifier.volume 21 en_US
dc.identifier.startpage 477 en_US
dc.identifier.endpage 481 en_US


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