DSpace Repository

The Effect of Hippophae rhamnoides Extract on Oxidative Damage on Rat's Gastric Tissue Depending on Co-Implementation of Methotrexate and Indomethacin

Show simple item record

dc.contributor.author 0000-0001-9453-5425
dc.contributor.author Altuner, Durdu
dc.contributor.author Cetin, Nihal
dc.contributor.author Demiryilmaz, Ismail
dc.contributor.author Kisaoglu, Abdullah
dc.contributor.author Kunak, Semih C.
dc.contributor.author Kurt, Nezahat
dc.contributor.author Ozogul, Bunyami
dc.contributor.author Sener, Ebru
dc.contributor.author Suleyman, Halis
dc.contributor.author Ucuncu, Yilmaz
dc.contributor.author Yilmaz, Ismayil
dc.date.accessioned 2022-08-17T06:01:13Z
dc.date.available 2022-08-17T06:01:13Z
dc.date.issued 2014
dc.identifier.uri http://www.latamjpharm.org/resumenes/33/3/LAJOP_33_3_1_14.pdf
dc.identifier.uri http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2473
dc.description.abstract The effect of Hippophae rhamnoides (HR) extract on oxidative damage on rat's gastric tissue depending on co-implementation of methotrexate (MTX) and indomethacin (IND) was investigated biochemically and histopathologically. HR extract was given to HR extract-given (HRIM) group of rats with dose of 50 mg/kg, and to IND+MTX-implemented rat group (IMG) orally with distilled water through catheter. One hour after, IND and MTX combination was given to HRIM and IMG groups orally for 7 days with dose of 5 mg/kg. In gastric tissues of IMG group, the MDA amount increased to healthy-sham (SG) and HRIM groups. The amount of tGSH, in IMG group's gastric tissue decreased to SG and HRIM groups. Serious focal erosions, sub-mucosal edemas and mixed-type inflammatory cell infiltrations have been observed on surface epithelium of histopathological sections of stomachs of IMG group. HR extract prevent the gastric damage in rats' gastric tissues, which was formed by MTX and IND combination. en_US
dc.language.iso eng en_US
dc.publisher COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRESDEPT CIENTIFICO, CALLE 5 NO 966, LA PLATA 00000, ARGENTINA en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Gastric tissue, Hippophae rhamnoides, Indomethacin, Methotrexate, Rat. en_US
dc.title The Effect of Hippophae rhamnoides Extract on Oxidative Damage on Rat's Gastric Tissue Depending on Co-Implementation of Methotrexate and Indomethacin en_US
dc.type article en_US
dc.contributor.department Ordu Üniversitesi en_US
dc.contributor.authorID 0000-0001-5646-7484 en_US
dc.contributor.authorID 0000-0001-7894-3613 en_US
dc.contributor.authorID 0000-0002-1685-5332 en_US
dc.contributor.authorID 0000-0003-2231-3967 en_US
dc.contributor.authorID 0000-0003-3233-8009 en_US
dc.identifier.volume 33 en_US
dc.identifier.issue 3 en_US
dc.identifier.startpage 453 en_US
dc.identifier.endpage 458 en_US


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account