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Evaluation of the effects of concentrated growth factors or advanced platelet rich-fibrin on postoperative pain, edema, and trismus following lower third molar removal: A randomized controlled clinical trial

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dc.contributor.author Kahveci, K.
dc.contributor.author Omezli, M. M.
dc.contributor.author Torul, D.
dc.date.accessioned 2022-08-16T05:24:15Z
dc.date.available 2022-08-16T05:24:15Z
dc.date.issued 2020
dc.identifier.uri http://doi.org/10.1016/j.jormas.2020.02.004
dc.identifier.uri http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1547
dc.description.abstract Background: The aim of this study was to investigate the effects of concentrated growth factors (CGF) and advanced platelet-rich fibrin (A-PRF) on edema, pain, and trismus after mandibular third molar surgery. Material and methods: Patients were randomly divided into A-PRF, CGF and control groups. After extraction of the third molars, A-PRF and CGF were prepared and applied to the extraction sockets in study groups, while nothing was applied to the control group. Edema was measured from 5 reference points, including tragus, labial commissure, soft tissue pogonion, lateral corner of the eye/lateral canthus and angulus mandible. Trismus measured as the distance between the right lower and upper central incisors. Trismus and edema were measured preoperatively, and on postoperative 2nd and 7th days. Pain evaluated using the visual analogue scale (VAS) between 6th hour and 7th day after surgery. Results: A total of 75 patients, 25 in each group, were included in the study. The change in tragus to labial commissure measurements showed a significant difference between baseline-7th days among control and CGF groups (P = 0.038). Significant differences observed between the tragus to pogonion measurements at baseline-7th days among the control-CGF groups (P = 0.014), and A-PRF-CGF groups (P = 0.038). Secondary outcome variables trismus, pain, and analgesic consumption showed no significant differences among the groups (P > 0.05). Conclusions: Based on the results of this study, it can be concluded that A-PRF and CGF seem to have no positive effects on pain, edema, and trismus after third molar surgery. (C) 2020 Elsevier Masson SAS. All rights reserved. en_US
dc.language.iso eng en_US
dc.publisher ELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS en_US
dc.relation.isversionof 10.1016/j.jormas.2020.02.004 en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Platelet-rich biomaterials; Third molar surgery; Pain; Swelling; Trismus en_US
dc.title Evaluation of the effects of concentrated growth factors or advanced platelet rich-fibrin on postoperative pain, edema, and trismus following lower third molar removal: A randomized controlled clinical trial en_US
dc.type article en_US
dc.relation.journal JOURNAL OF STOMATOLOGY ORAL AND MAXILLOFACIAL SURGERY en_US
dc.contributor.department Ordu Üniversitesi en_US
dc.contributor.authorID 0000-0003-2323-606X en_US
dc.identifier.volume 121 en_US
dc.identifier.issue 6 en_US
dc.identifier.startpage 646 en_US
dc.identifier.endpage 651 en_US


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