Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/5158
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dc.contributor.authorKacar, Ayper-
dc.contributor.authorDemir, Haci Ahmet-
dc.contributor.authorDurak, Haydar-
dc.contributor.authorDervisoglu, Sergulen-
dc.date.accessioned2024-03-26T06:41:55Z-
dc.date.available2024-03-26T06:41:55Z-
dc.date.issued2013-
dc.identifier.citationKaçcr, A., Demir, HA., Durak, H., Dervisoglu, S. (2013). Spindle Cell Rhabdomyosarcoma Displaying CD34 Positivity: A Potential Diagnostic Pitfall; Report of Two Pediatric Cases. Turk. J. Pathol., 29(3), 221-226. https://doi.org/10.5146/tjpath.2013.01181en_US
dc.identifier.issn1018-5615-
dc.identifier.issn1309-5730-
dc.identifier.urihttp://dx.doi.org/10.5146/tjpath.2013.01181-
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000217458500011-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/5158-
dc.descriptionWoS Categories: Pathologyen_US
dc.descriptionWeb of Science Index: Emerging Sources Citation Index (ESCI)en_US
dc.descriptionResearch Areas: Pathologyen_US
dc.description.abstractSpindle cell rhabdomyosarcoma is a rare subtype of rhabdomyo-sarcoma mainly seen in children. Occasional aberrant staining with a variety of immunohistochemical markers has been noted. The aberrantly expressed markers include alpha-smooth muscle actin, cytokeratin, S100, neurofilaments, CD20, immunoglobins, and CD117. We report herein two pediatric cases displaying strong CD34 positivity and one with additional focal CD117 positivity, causing considerable difficulty in distinction from solitary fibrous tumor and extra-gastrointestinal stromal tumor. To our knowledge, CD34 staining has been merely reported in rhabdomyosarcoma. Spindle cell rhabdomyosarcoma has to be considered in the differential diagnosis of childhood spindle cell tumors. Post-chemotherapy specimens should be evaluated in caution, since chemotherapy can cause considerable changes in tumor antigen expression. Since CD117 and CD34 are stem cell markers, their positivity in pediatric tumors should be interpreted with caution. Even if the morphology is not supportive, a wide immunohistochemical panel should be applied in childhood malignant solid tumors.en_US
dc.language.isoengen_US
dc.publisherDE GRUYTER OPEN LTD-WARSAWen_US
dc.relation.isversionof10.5146/tjpath.2013.01181en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectRhabdomyosarcoma, Antigens, CD34, Differential diagnosisen_US
dc.titleSpindle Cell Rhabdomyosarcoma Displaying CD34 Positivity: A Potential Diagnostic Pitfall; Report of Two Pediatric Casesen_US
dc.typearticleen_US
dc.relation.journalTURKISH JOURNAL OF PATHOLOGYen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.identifier.volume29en_US
dc.identifier.issue3en_US
dc.identifier.startpage221en_US
dc.identifier.endpage226en_US
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