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http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/4833
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DC Field | Value | Language |
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dc.contributor.author | Kaya, Yasemin | - |
dc.contributor.author | Gulcu, Oktay | - |
dc.contributor.author | Aksakal, Emrah | - |
dc.contributor.author | Kalkan, Kamuran | - |
dc.contributor.author | Aydin, Sidar S. | - |
dc.contributor.author | Kaya, Ahmet | - |
dc.contributor.author | Bostan, Sedat | - |
dc.date.accessioned | 2024-03-20T13:51:48Z | - |
dc.date.available | 2024-03-20T13:51:48Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Kaya, Y., Gülcü, O., Aksakal, E., Kalkan, K., Aydin, SS., Kaya, A., Bostan, S. (2023). A significant predictor of in-hospital and long-term mortality and progression in COVID-19 patients: The end-stage liver disease (MELD) score model. J. Med. Virol., 95(1). https://doi.org/10.1002/jmv.28109 | en_US |
dc.identifier.issn | 0146-6615 | - |
dc.identifier.issn | 1096-9071 | - |
dc.identifier.uri | http://dx.doi.org/10.1002/jmv.28109 | - |
dc.identifier.uri | https://www.webofscience.com/wos/woscc/full-record/WOS:000852296300001 | - |
dc.identifier.uri | http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/4833 | - |
dc.description | WoS Categories: Virology | en_US |
dc.description | Web of Science Index: Science Citation Index Expanded (SCI-EXPANDED) | en_US |
dc.description | Research Areas: Virology | en_US |
dc.description.abstract | The aim of this study is to investigate the relationship between the model for end-stage liver disease (MELD) score and disease progression and mortality in COVID-19 patients. The files of 4213 patients over the age of 18 who were hospitalized with the diagnosis of COVID-19 between March 20, 2020 and May 1, 2021 were retrospectively scanned. Sociodemographic characteristics, chronic diseases, hemogram and biochemical parameters at the time they were diagnosed with COVID-19 of the patients, duration of hospitalization, duration of intensive care unit (ICU), duration of intubation, in-hospital mortality from COVID-19 and outside-hospital mortality for another reason (within the last 1 year) and recurrent hospitalization (within the last 1 year) were recorded. The MELD scores of the patients were calculated. Two groups were formed as MELD score < 10 and MELD score >= 10. The rate of ICU, in-hospital mortality from COVID-19 and outside-hospital mortality from other causes, intubation rate, and recurrent hospitalization were significantly higher in the MELD >= 10 group. The duration of ICU, hospitalization, intubation were significantly higher in the MELD >= 10 group (p < 0.001). As a result of Univariate and Multivariate analysis, MELD score was found to be the independent predictors of ICU, in-hospital mortality, intubation, and recurrent hospitalization (p < 0.001). MELD score 18.5 predicted ICU with 99% sensitivity and 100% specificity (area under curve [AUC]: 0.740, 95% confidence interval [CI]: 0.717-0.763, p < 0.001) also MELD score 18.5 predicted in-hospital mortality with 99% sensitivity and 100% specificity (AUC: 0.797, 95% CI: 0.775-0.818, p < 0.001). The MELD score was found to be the independent predictors of in-hospital mortality, ICU admission, and intubation in COVID-19 patients. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | WILEY-HOBOKEN | en_US |
dc.relation.isversionof | 10.1002/jmv.28109 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | COVID-19, intensive care unit admission, in-hospital mortality | en_US |
dc.subject | HEPATIC-DYSFUNCTION, SEVERITY, RISK | en_US |
dc.title | A significant predictor of in-hospital and long-term mortality and progression in COVID-19 patients: The end-stage liver disease (MELD) score model | en_US |
dc.type | article | en_US |
dc.relation.journal | JOURNAL OF MEDICAL VIROLOGY | en_US |
dc.contributor.department | Ordu Üniversitesi | en_US |
dc.contributor.authorID | 0000-0002-8204-1505 | en_US |
dc.contributor.authorID | 0000-0001-5765-4281 | en_US |
dc.contributor.authorID | 0000-0001-7360-8090 | en_US |
dc.contributor.authorID | 0000-0001-9845-7938 | en_US |
dc.identifier.volume | 95 | en_US |
dc.identifier.issue | 1 | en_US |
Appears in Collections: | Dahili Tıp Bilimleri |
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