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DC Field | Value | Language |
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dc.contributor.author | Cirrik, Selma | - |
dc.contributor.author | Kabartan CokelI, Emel | - |
dc.contributor.author | Gulec Peker, Emine Gulceri | - |
dc.contributor.author | Hacioglu, Gulay | - |
dc.date.accessioned | 2024-03-15T12:08:12Z | - |
dc.date.available | 2024-03-15T12:08:12Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Cirrik, S., CokelI, EK., Peker, EGG., Hacioglu, G. (2023). The effects of propolis on doxorubicin-induced hepatorenal damage: a comparison of ethanolic and oily extracts of propolis. CyTA-J. Food, 21(1), 666-673. https://doi.org/10.1080/19476337.2023.2274370 | en_US |
dc.identifier.issn | 1947-6337 | - |
dc.identifier.issn | 1947-6345 | - |
dc.identifier.uri | http://dx.doi.org/10.1080/19476337.2023.2274370 | - |
dc.identifier.uri | https://www.webofscience.com/wos/woscc/full-record/WOS:001098232600001 | - |
dc.identifier.uri | http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/4640 | - |
dc.description | WoS Categories: Food Science & Technology | en_US |
dc.description | Web of Science Index: Science Citation Index Expanded (SCI-EXPANDED) | en_US |
dc.description | Research Areas: Food Science & Technology | en_US |
dc.description.abstract | The protective effect of ethanolic propolis extract (PE) in the toxic effects of doxorubicin (DOX), a chemotherapy drug, has been reported previously. Since ethanol usage has some restrictions, in the present study, olive oil as an alternative to ethanol has been tested in DOX-induced hepatorenal injury and the effectiveness of the two extracts were compared. Male rats were orally given PE or oily propolis extract (PO) for 15 days (50 mg/kg/day) and DOX was injected (15 mg/kg, intraperitoneally) on the 13th day. The animals were sacrificed and then hepatorenal oxidative stress and functional parameters were evaluated. DOX-induced reduction in hepatorenal functions and oxidative stress were significantly reduced in both propolis treatment groups. Treatment with PO was more effective in reducing DOX-induced oxidative stress, yet both extracts showed similar efficacy in improving hepatorenal functions. We suggest that the PO could be preferred to avoid the side effects of ethanol. | en_US |
dc.description.sponsorship | Ordu University [A-2006/ A-2101] | en_US |
dc.language.iso | eng | en_US |
dc.publisher | TAYLOR & FRANCIS LTD-ABINGDON | en_US |
dc.relation.isversionof | 10.1080/19476337.2023.2274370 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Oily propolis extract, ethanolic propolis extract, doxorubicin, oxidative stress, kidney, liver | en_US |
dc.subject | ANTIOXIDANT ACTIVITY | en_US |
dc.title | The effects of propolis on doxorubicin-induced hepatorenal damage: a comparison of ethanolic and oily extracts of propolis | en_US |
dc.type | article | en_US |
dc.relation.journal | CYTA-JOURNAL OF FOOD | en_US |
dc.contributor.department | Ordu Üniversitesi | en_US |
dc.contributor.authorID | 0000-0002-6289-2310 | en_US |
dc.contributor.authorID | 0000-0001-7244-0281 | en_US |
dc.identifier.volume | 21 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 666 | en_US |
dc.identifier.endpage | 673 | en_US |
Appears in Collections: | Temel Tıp Bilimleri |
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