Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/4291
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dc.contributor.authorKuralay, Filiz-
dc.contributor.authorDukar, Nilgun-
dc.date.accessioned2024-03-15T08:37:35Z-
dc.date.available2024-03-15T08:37:35Z-
dc.date.issued2020-
dc.identifier.citationKuralay, F., Dükar, N. (2020). Polypyrrole-Based Nanohybrid Electrodes: Their Preparation and Potential Use for DNA Recognition and Paclitaxel Quantification. ChemistrySelect, 5(15), 4708-4714. https://doi.org/10.1002/slct.201904253en_US
dc.identifier.issn2365-6549-
dc.identifier.urihttp://dx.doi.org/10.1002/slct.201904253-
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000528045700042-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/4291-
dc.descriptionWoS Categories: Chemistry, Multidisciplinaryen_US
dc.descriptionWeb of Science Index: Science Citation Index Expanded (SCI-EXPANDED)en_US
dc.descriptionResearch Areas: Chemistryen_US
dc.description.abstractFabrication of conducting polymer networks based on polypyrrole/multi-walled carbon nanotubes (PPy/MWCNTs) modified graphite electrodes that were achieved with a single-step electropolymerization and potential use of these electrodes for deoxyribonucleic acid (DNA) recognition and anticancer drug (Paclitaxel, PTX) quantification were presented in the present work. PPy/MWCNTs nanohybrid PGEs were constructed in aqueous solution of pyrrole (Py) and MWCNTs using cyclic voltammetry (CV) and constant potential electrolysis. So-formed electrodes were characterized with cyclic voltammetry and electrochemical impedance spectroscopy (EIS). Surface morphologies of the surfaces were investigated by scanning electron microscopy (SEM) studies. Bio-application of the PPy/MWCNTs nanohybrid modified PGEs were accomplished by subjecting them to double-stranded DNA (dsDNA) modification for direct DNA recognition and PTX determination. For the drug determination, interaction of DNA-based electrodes with PTX was investigated. Detection limit was found as 1.55 x 10(-8) M based on the changes in the oxidation of guanine base which made the proposed electrode convenient for clinical trials.en_US
dc.language.isoengen_US
dc.publisherWILEY-V C H VERLAG GMBH-WEINHEIMen_US
dc.relation.isversionof10.1002/slct.201904253en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectanticancer drug, dsDNA, electrochemical deposition, polymer nanohybrids, polypyrroleen_US
dc.subjectCONDUCTING POLYMER-FILM, ELECTROCHEMICAL SENSORS, NANOCOMPOSITE, BIOSENSOR, IMPEDANCE, COATINGSen_US
dc.titlePolypyrrole-Based Nanohybrid Electrodes: Their Preparation and Potential Use for DNA Recognition and Paclitaxel Quantificationen_US
dc.typearticleen_US
dc.relation.journalCHEMISTRYSELECTen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0003-0356-9692en_US
dc.identifier.volume5en_US
dc.identifier.issue15en_US
dc.identifier.startpage4708en_US
dc.identifier.endpage4714en_US
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