Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/4224
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dc.contributor.authorCirakli, Alper-
dc.contributor.authorErdem, Havva-
dc.date.accessioned2024-03-15T08:29:09Z-
dc.date.available2024-03-15T08:29:09Z-
dc.date.issued2023-
dc.identifier.citationÇirakli, A., Erdem, H. (2023). Hazelnut Has Potency on Wound Healing Associated with Immunohistochemical Biomarkers. Indian J. Pharm. Educ. Res., 57(3), 748-755. https://doi.org/10.5530/ijper.57.3.91en_US
dc.identifier.issn0019-5464-
dc.identifier.urihttp://dx.doi.org/10.5530/ijper.57.3.91-
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:001137492300001-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/4224-
dc.descriptionWoS Categories: Education, Scientific Disciplines; Pharmacology & Pharmacyen_US
dc.descriptionWeb of Science Index: Science Citation Index Expanded (SCI-EXPANDED)en_US
dc.descriptionResearch Areas: Education & Educational Research; Pharmacology & Pharmacyen_US
dc.description.abstractBackground: In this study, it was aimed to evaluate the impact of hazelnut on wound healing by using its immunohistochemical impacts on Claudin-5, Tumor Necrosis Factor-alpha (TNF-alpha), tumor Protein-63 (p63), and Insulin-like Growth Factor-1 (IGF-1) expression. Materials and Methods: Seventy-two male Wistar-Albino rats were used. Nine groups with 8 rats each group, and 3, 7, and 14 days groups were formed as oral, local, and control groups. Samples obtained from rats were evaluated with these immunohistochemical biomarkers. Results: Claudin-5 scores were found to be statistically significant in the oral group on all days (p=0.007, p=0.002, p=0,014). TNF-alpha scores were found to be statistically significant on the 3(rd) and 7(th) days in the local and oral groups (p=0.040, p=0.001). p63 scores were found to be statistically significant in the oral group when looking at the 14(th) day values (p=0.007). IGF-1 scores were found to be statistically significant on the 7(th) and 14(th) days in the local group (p=0.040). Conclusion: It was determined that hazelnut has positive impact on wound healing by stimulating the claudin-5, TNF-a, p63, and IGF-1 expression levels.en_US
dc.description.sponsorshipMedical Faculty of Ordu Universityen_US
dc.language.isoengen_US
dc.publisherASSOC PHARMACEUTICAL TEACHERS INDIA-BANGALOREen_US
dc.relation.isversionof10.5530/ijper.57.3.91en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectWound, Healing, Hazelnut, Immunohistochemical, Biomarkersen_US
dc.subjectGROWTH-FACTOR-I, EXPRESSIONen_US
dc.titleHazelnut Has Potency on Wound Healing Associated with Immunohistochemical Biomarkersen_US
dc.typearticleen_US
dc.relation.journalINDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCHen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.identifier.volume57en_US
dc.identifier.issue3en_US
dc.identifier.startpage748en_US
dc.identifier.endpage755en_US
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