Please use this identifier to cite or link to this item:
http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3611
Title: | Designing functional materials: DNA/Poly(3,4-ethylenedioxythiophene) interfaces for advanced DNA direct electrochemistry and DNA-Drug interaction detection |
Authors: | Kuralay, Filiz Dukar, Nilgun Bayramli, Yasar Ordu Üniversitesi |
Keywords: | PENCIL-GRAPHITE ELECTRODE; CARBON NANOTUBES; POLY 3,4-ETHYLENEDIOXYTHIOPHENE; DISPOSABLE ELECTRODES; GRAPHENE OXIDE; STRAIN SENSOR; URIC-ACID; BIOSENSORS; COMPOSITE; NANOCOMPOSITE Functional surfaces; dsDNA; DNA-anticancer drug interaction; Electrochemistry |
Issue Date: | 2021 |
Publisher: | ELSEVIER AMSTERDAM |
Citation: | Kuralay, F., Dukar, N., Bayramli, Y. (2021). Designing functional materials: DNA/Poly(3,4-ethylenedioxythiophene) interfaces for advanced DNA direct electrochemistry and DNA-Drug interaction detection. Materials Science and Engineering B-Advanced Functional Solid-State Materials, 272, -.Doi:10.1016/j.mseb.2021.115382 |
Abstract: | In the present study, preparation of poly(3,4-ethylenedioxythiophene) coated pencil graphite electrode with the addition of multi-walled carbon nanotubes (MWCNTs) (PEDOT nanoelectrode, NE); incorporation of double-stranded deoxyribonucleic acid (dsDNA) onto NE (dsDNA/PEDOT NE); and the bio-application of dsDNA/PEDOT NE were described. PEDOT NEs were first used to immobilize dsDNA onto the electrode surfaces in a high efficiency to detect dsDNA with advanced oxidation signals. Afterwards, these functional biointerfaces were used for the investigation of DNA interaction with Mitomycin C (MC) and Paclitaxel (PTX) based on guanine and adenine oxidation signals. dsDNA/PEDOT NE was presented a linearity in the concentration of 1 mg L-1 to 50 mg L-1 for MC with a detection limit of 0.26 mg L-1 . The linear range was between 0.5 mg L-1 and 60 mg L-1 for PTX with a detection limit of 0.14 mg L-1 (n = 3). In addition, dsDNA/PEDOT NE was presented good stability. |
Description: | WoS Categories : Materials Science, Multidisciplinary; Physics, Condensed Matter Web of Science Index : Science Citation Index Expanded (SCI-EXPANDED) Research Areas : Materials Science; Physics |
URI: | http://dx.doi.org/10.1016/j.mseb.2021.115382 https://www.webofscience.com/wos/woscc/full-record/WOS:000686131900005 http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3611 |
ISBN: | 0921-5107 1873-4944 |
Appears in Collections: | Kimya |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.