Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3195
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dc.contributor.authorIkinci, Ayse-
dc.contributor.authorOdaci, Ersan-
dc.contributor.authorBas, Orhan-
dc.date.accessioned2022-09-06T12:21:31Z-
dc.date.available2022-09-06T12:21:31Z-
dc.date.issued2013-
dc.identifier.urihttp://doi.org/10.3906/sag-1202-68-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/3195-
dc.description.abstractAim: Since ethyl pyruvate (EP) is a known neuroprotective agent, this study was intended to investigate the effects of EP on pyramidal cell numbers and morphology in the hippocampus cornu ammonis after brain ischemia. Materials and methods: Female rats were divided into 5 groups: control, ischemia, ischemia + EP, incision + EP, and incision + Ringer's lactate (groups I, II, III, IV, and V, respectively). No intervention was performed in group I. Ischemia was established in groups II and III, and neck incisions were performed in groups IV and V. EP was intraperitoneally injected in groups III and IV. Ringer's lactate was also administered to group V. Brains were evaluated stereologically and histopathologically. Results: The total number of pyramidal cells in group II was significantly lower than those in groups I, IV, and V. The total number of pyramidal cells in group III was significantly lower than those in groups I and IV. Conclusion: Ischemia reduces the number of pyramidal cells in the cornu ammonis, and EP has no effect on the number of pyramidal cells in the 16-week-old female rat cornu ammonis after brain ischemia.en_US
dc.language.isoengen_US
dc.publisherTUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEYATATURK BULVARI NO 221, KAVAKLIDERE, ANKARA 00000, TURKEYen_US
dc.relation.isversionof10.3906/sag-1202-68en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEthyl pyruvate, hippocampus, ischemia, stereology, raten_US
dc.titleEffects of ethyl pyruvate administration on female rats' pyramidal cells of cornu ammonis after brain ischemia: a stereological and histopathological studyen_US
dc.typearticleen_US
dc.relation.journalTURKISH JOURNAL OF MEDICAL SCIENCESen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0002-7449-2699en_US
dc.identifier.volume43en_US
dc.identifier.issue3en_US
dc.identifier.startpage354en_US
dc.identifier.endpage361en_US
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