Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2561
Full metadata record
DC FieldValueLanguage
dc.contributor.authorKuralay, Filiz-
dc.date.accessioned2022-08-17T06:45:18Z-
dc.date.available2022-08-17T06:45:18Z-
dc.date.issued2017-
dc.identifier.urihttps://doi.org/10.1002/9781119242659-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2561-
dc.description.abstractDeoxyribonucleic acid (DNA) is one of the most important molecules of life since it carries heritage information and instructs the biological synthesis of proteins and enzymes through the process of replication and transcription of genetic information, both in living organisms and in many viruses. Detection of DNA sequences receives much attention. It plays a major role in clinical, forensic, environmental, food, and pharmaceutical applications. It is also important to understand the structural properties of DNA and the action mechanism of some antitumor and antivirus drugs to design new and more efficient DNA-targeted drugs. Among many DNA detection methods, electrochemical ones, which have many advantages over time-consuming traditional methods, are very favorable. Electrochemistry offers sensitive, accurate, simple, and low-cost analysis. Thus, electrochemical biosensors have classified as one of the most used biosensor types in terms of detecting DNA, DNA hybridization, and DNA-anticancer drug interaction biosensing. The genetic information is encoded as a sequence of nucleotides named as guanine (G), adenine (A), thymine (T), and cytosine (C) which are electroactive. This makes electrochemistry very attractive for DNA detection. Furthermore, in order to enhance the signals of DNA bases, various platforms such as conducting polymers and nanomaterials are used. Conducting polymers-based approaches provides suitable immobilization surface for DNA by increasing the electroactive surface area of the electrode material. In addition, they serve as robust and stable surfaces.en_US
dc.language.isoengen_US
dc.publisherSCRIVENER PUBLISHING LLC, 100 CUMMINGS CENTER, STE 541J, BEVERLY, MA 01915-6106 USAen_US
dc.relation.isversionof10.1002/9781119242659en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDNA; DNA detection; conducting polymer; electrochemical biosensoren_US
dc.subjectSINGLE-STRANDED-DNA; LABEL-FREE; NUCLEIC-ACIDS; FUNCTIONALIZED GRAPHENE; CATIONIC POLYTHIOPHENE; VOLTAMMETRIC DETECTION; HYBRIDIZATION; CARBON; POLYPYRROLE; SENSORen_US
dc.titleConducting Polymer-based Electrochemical DNA Biosensingen_US
dc.typearticleen_US
dc.relation.journalADVANCED ELECTRODE MATERIALSen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0003-0356-9692en_US
dc.identifier.startpage485en_US
dc.identifier.endpage500en_US
Appears in Collections:Kimya

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.