Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2528
Title: The beneficial effects of subcutaneous Allium cepa injection on random flap survival in rats
Authors: Altinel, Dincer
Biltekin, Burcu
Celikten, Mert
Erdem, Havva
Oruc, Eymen
Serin, Merdan
Toplu, Gaye
Yazar, Sevgi Kurt
Ordu Üniversitesi
Keywords: Allium cepa; random flaps; rat
Issue Date: 2019
Publisher: TAYLOR & FRANCIS LTD, 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND
Abstract: Random flaps are frequently used in the practice of reconstructive surgery. The aim of this experimental study was to investigate the effects of Allium cepa on random flap survival in rats. Fourteen Wistar rats were used for this experimental study. The subjects were divided into experiment and control groups. Rats in the experiment group received daily injections of A. cepa extract for 7 d before the elevation of the flaps. Following the treatmentperiod, elevation and reinsertion of the dorsal flaps were performed. Necrotic and total flaps areas were marked and calculated 7 d after the flap elevation. Histological examinations and microangiography were performed to evaluate the results. The mean value of the proportion of necrotic flap areas to the total flap area was 25.06 and 50.6% in the A. cepa and control group, respectively (p = .0079). In the histological examination, number of vessels identified in the dermis were 23.75 +/- 0.7 and 33.75 +/- 9 in the A. cepa and control group, respectively (p = .7457). In angiographic images, vessels formations were more noticeable in the A. cepa group. We conclude that preoperative subcutaneous A. cepa injection increases dorsal flap survival in rats.
URI: http://doi.org/10.1080/2000656X.2019.1597371
http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2528
Appears in Collections:Cerrahi Tıp Bilimleri

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.