Please use this identifier to cite or link to this item:
http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2289
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Aslan, Ali | - |
dc.contributor.author | Bas, Orhan | - |
dc.contributor.author | Cankaya, Soner | - |
dc.contributor.author | Hanci, Hatice | - |
dc.contributor.author | Kaya, Yasemin | - |
dc.contributor.author | Nalbant, Ismail | - |
dc.contributor.author | Odaci, Ersan | - |
dc.contributor.author | Uydu, Huseyin Avni | - |
dc.date.accessioned | 2022-08-17T05:27:42Z | - |
dc.date.available | 2022-08-17T05:27:42Z | - |
dc.date.issued | 2018 | - |
dc.identifier.uri | http://doi.org/10.1080/0886022X.2018.1489289 | - |
dc.identifier.uri | http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2289 | - |
dc.description.abstract | Purpose: Today, the long-term effects of partial exposure of cholinesterase on the kidney continue to be a research topic. In this study, we aimed to histopathologically investigate the possible effect of acute toxicity due to fenthion, an organophosphate (OP) compound, on the kidneys. Methods: In all, 21 rats were randomly divided into three groups. Experimental group was each administered intraperitoneal 0.8 g/kg fenthion within physiologic serum. Sham group was only administered intraperitoneal physiologic serum. The control group continued normal nutrition with no procedure performed. After 24 h, all rats were sacrificed by cervical dislocation. Half of the recipient kidney tissues were examined histopathologically and the other half biochemically. Results: No histopathological findings were found in the control group. Rats in the experimental group were observed to have epithelial cell disorganization in tubules, moderate epithelial cell loss, and degeneration. Again, expansion of tubules, vacuolization of tubular epithelial cells, and tubular structure approaching atrophy were observed, with cells approaching apoptosis and common hemorrhage noted although rats in the sham group were observed to have mild tubular degeneration. Conclusions: It should not be forgotten that one of the causes of systemic complaints linked to acute toxicity exposed to the OP compound of fenthion may be cellular injury to glomerular and tubular structures in the kidneys. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | TAYLOR & FRANCIS LTD, 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND | en_US |
dc.relation.isversionof | 10.1080/0886022X.2018.1489289 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Organophosphate; fenthion; renal injury; poisoning; histopathological investigation | en_US |
dc.title | Acute renal involvement in organophosphate poisoning: histological and immunochemical investigations | en_US |
dc.type | article | en_US |
dc.relation.journal | RENAL FAILURE | en_US |
dc.contributor.department | Ordu Üniversitesi | en_US |
dc.contributor.authorID | 0000-0001-7360-8090 | en_US |
dc.contributor.authorID | 0000-0001-8056-1892 | en_US |
dc.contributor.authorID | 0000-0002-8715-9932 | en_US |
dc.contributor.authorID | 0000-0002-9674-5618 | en_US |
dc.identifier.volume | 40 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 410 | en_US |
dc.identifier.endpage | 415 | en_US |
Appears in Collections: | Dahili Tıp Bilimleri |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.