Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2111
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dc.contributor.authorAkturk, Zeynep-
dc.contributor.authorBas, Orhan-
dc.contributor.authorCanpolat, Sinan-
dc.contributor.authorColakoglu, Serdar-
dc.contributor.authorIkinci, Ayse-
dc.contributor.authorOdaci, Ersan)-
dc.contributor.authorSonmez, Osman Fikret-
dc.date.accessioned2022-08-16T12:05:13Z-
dc.date.available2022-08-16T12:05:13Z-
dc.date.issued2014-
dc.identifier.urihttp://doi.org/10.3906/sag-1305-40-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/2111-
dc.description.abstractBackground/aim: This study investigated the effect of Ginkgo biloba (GB) on brain volume in cerebral ischemia induced by stopping carotid artery blood flow. Materials and methods: Twenty-four adult male rats were divided into 4 groups of 6 rats each. No procedure was performed on the control group. Ischemia was applied to the rats in the ischemia and ischemia + GB groups by clamping the arteria carotis communis for 30 min. The rats in the ischemia + GB group were given 100 mg/kg drops (Tebokan Fort Drop, Abdi Ibrahim Ilac Sanayi A.S., Turkey) containing dry GB leaf extract orally, every day for 14 days from the day of ischemia. In the sham group, surgical stress alone was applied by performing a skin incision. On the 14th day, brain tissues were extracted and evaluated stereologically and histopathologically. Results: The only statistically significant difference was observed between the sham and control groups. Conclusion: This result may be interpreted as surgical stress, established by cutaneous incision, having an adverse effect on brain volume. Additionally, the absence of any difference in terms of brain volume following 30 min of ischemia between the ischemia and control groups suggests that a probable postischemic rise in brain volume disappears within 14 days.en_US
dc.language.isoengen_US
dc.publisherTUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEYATATURK BULVARI NO 221, KAVAKLIDERE, ANKARA 00000, TURKEYen_US
dc.relation.isversionof10.3906/sag-1305-40en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGinkgo biloba brain ischemia rat stereologyen_US
dc.titleEffect of Ginkgo biloba on brain volume after carotid artery occlusion in rats: a stereological and histopathological studyen_US
dc.typearticleen_US
dc.relation.journalTURKISH JOURNAL OF MEDICAL SCIENCESen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0002-7449-2699en_US
dc.identifier.volume44en_US
dc.identifier.issue4en_US
dc.identifier.startpage546en_US
dc.identifier.endpage553en_US
Appears in Collections:Temel Tıp Bilimleri

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