Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1975
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dc.contributor.authorErgun, Sercan-
dc.contributor.authorPetrovic, Nina-
dc.date.accessioned2022-08-16T11:38:43Z-
dc.date.available2022-08-16T11:38:43Z-
dc.date.issued2018-
dc.identifier.urihttp://doi.org/10.1007/s40291-017-0314-8-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1975-
dc.description.abstractStandard cancer therapies for solid malignancies, such as chemotherapy and radiotherapy, are not target specific against cancer cells and are often not fully efficacious. Chemotherapy and radiotherapy may cause side effects, and the need to develop additional strategies for cancer treatment is urgent. MicroRNAs (miRNAs) are small non-coding RNAs with heterogeneous functions and have been described in almost every known cancer model. Besides their basic tumor-suppressive and oncogenic functions, they also have the potential to modulate chemotherapy and radiotherapy and to be manipulated with chemical compounds to make them chemically suitable for efficient delivery to cancer cells. It has been suggested that the level of expression of specific miRNAs could increase treatment efficacy by determining the stage of chemotherapy/radiotherapy sensitivity. Application of miRNAs alone or in combination with standard therapeutic strategies may significantly improve the success of cancer treatments in the future.en_US
dc.language.isoengen_US
dc.publisherADIS INT LTD, 5 THE WAREHOUSE WAY, NORTHCOTE 0627, AUCKLAND, NEW ZEALANDen_US
dc.relation.isversionof10.1007/s40291-017-0314-8en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMICRORNA; EXPRESSION; RESISTANCE; DELIVERY; MIR-21; GROWTH; CELLS; NANOPARTICLES; PROLIFERATION; CHEMOTHERAPYen_US
dc.titlemiRNAs as Potential Treatment Targets and Treatment Options in Canceren_US
dc.typearticleen_US
dc.relation.journalMOLECULAR DIAGNOSIS & THERAPYen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0002-6733-9848en_US
dc.contributor.authorID0000-0003-2503-1228en_US
dc.identifier.volume22en_US
dc.identifier.issue2en_US
dc.identifier.startpage157en_US
dc.identifier.endpage168en_US
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