1. Ordu Üniversitesi Açık Arşiv Sistemi
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  3. Sağlık Bilimleri Fakültesi
  4. Beslenme ve Diyetetik
Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1934
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dc.contributor.authorAltay, Diler Us-
dc.contributor.authorAlver, Ahmet-
dc.contributor.authorKaraguzel, Ersagun-
dc.contributor.authorKeha, Esref Edip-
dc.contributor.authorMentese, Ahmet-
dc.contributor.authorYaman, Serap Ozer-
dc.date.accessioned2022-08-16T11:29:48Z-
dc.date.available2022-08-16T11:29:48Z-
dc.date.issued2018-
dc.identifier.urihttp://doi.org/10.1590/S1677-5538.IBJU.2017.0404-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1934-
dc.description.abstractPurposes: The aim of this study was to determine the diagnostic significance of fibronectin type III domain containing protein 5 (FNDC5)/Irisin levels in the sera of patients with renal cell cancer. Materials and Methods: In the study, 48 individuals were evaluated. The patient group included 23 subjects diagnosed with renal tumor, and the control group of 25 healthy individuals. Patients diagnosed with renal tumor received surgical treatment consisting of radical or partial nephrectomy. Blood specimens were collected and serum FNDC5/Irisin and carcinoembryonic antigen (CEA) levels were determined using enzymelinked immunosorbent assay (ELISA). Results: FNDC5/irisin and CEA levels in renal cancer patients were significantly higher compared with the control group (p=0.0001, p=0.009, respectively). Also, FNDC5 levels was more sensitive and specific than CEA levels. The best cut-off points for FNDC5/irisin were > 105pg/mL and CEA were > 2.67ng/mL for renal cancer. Conclusions: FNDC5/Irisin may be used as a diagnostic biomarker for renal cancer.en_US
dc.language.isoengen_US
dc.publisherBRAZILIAN SOC UROL, RUA BAMBINA, 153, RIO DE JANEIRO, 2251-050, BRAZILen_US
dc.relation.isversionof10.1590/S1677-5538.IBJU.2017.0404en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCarcinoma; Renal Cell; FNDC5 protein; rat [Supplementary Concept]; Urologic Neoplasmsen_US
dc.titleThe diagnostic value of FNDC5/Irisin in Renal Cell Canceren_US
dc.typearticleen_US
dc.relation.journal44en_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0002-0465-8403en_US
dc.identifier.volume4en_US
dc.identifier.issue734en_US
dc.identifier.startpage739en_US
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