Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1678
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dc.contributor.authorGokmenoglu, C.-
dc.contributor.authorKara, C.-
dc.contributor.authorKara, N.-
dc.contributor.authorSelamet, H.-
dc.date.accessioned2022-08-16T06:00:47Z-
dc.date.available2022-08-16T06:00:47Z-
dc.date.issued2018-
dc.identifier.urihttp://doi.org/10.1111/cpr.12417-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1678-
dc.description.abstractObjectivesLow level laser therapy (LLLT), which stimulates natural biological processes in the application region, is frequently used in dental treatments. The aim of our study was to evaluate the effects of LLLT which could activate precancerous cells or increase existing cancerous tissue in case of clinically undetectable situations. Materials and methodsSaos-2 osteoblast-like osteosarcoma cells and A549 human lung carcinoma cells were used. Twenty-four hours after preparation of cell culture plates, laser irradiation was performed 1, 2 and 3 times according to the test groups using Nd:YAG laser with the power output 0.5, 1, 2 and 3W. Cell proliferation analysis was performed by MTT assay at the 24th hour following the last laser applications. ResultsGenerally, it was observed that the proliferation rates increased as the number of applications increased, when compared to the controls, especially in those cases in which the irradiation was performed 2 or 3 times more. ConclusionThe findings of this study have led to the conclusion that LLLT increases cancer cell proliferation, depending on the power output level of the laser and the number of applications. In addition to the proliferation and mitotic activity of the cancer tissue cells, we concluded that LLLT, which is frequently used in dental practice, could activate precancerous cells or increase existing cancerous tissue.en_US
dc.language.isoengen_US
dc.publisherWILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USAen_US
dc.relation.isversionof10.1111/cpr.12417en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectlow level laser therapy; lung carcinoma; Nd: YAG laser; osteosarcomaen_US
dc.titleLow level laser therapy induces increased viability and proliferation in isolated cancer cellsen_US
dc.typearticleen_US
dc.relation.journalCELL PROLIFERATIONen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0001-5356-3665en_US
dc.contributor.authorID0000-0002-3803-7189en_US
dc.contributor.authorID0000-0002-3803-7189en_US
dc.contributor.authorID0000-0003-3681-6143en_US
dc.identifier.volume51en_US
dc.identifier.issue2en_US
Appears in Collections:Periodontoloji

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