Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1672
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dc.contributor.authorCelen, Kubra-
dc.contributor.authorDede, Figen Ongoz-
dc.contributor.authorGokmenoglu, Ceren-
dc.contributor.authorKara, Cankat-
dc.contributor.authorKara, Nihal Belduz-
dc.date.accessioned2022-08-16T05:59:21Z-
dc.date.available2022-08-16T05:59:21Z-
dc.date.issued2020-
dc.identifier.urihttp://doi.org/10.1177/1535370220953771-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1672-
dc.description.abstractPatients with older age and pre-existing conditions like cardiovascular disease, hypertension, diabetes, and obesity are in the higher risk group for developing severe Covid-19 infections. The inflammatory pathways that are involved in these conditions are the same pathways that we see in periodontal diseases (PDs). This raises a significant question: Is PD a pre-existing condition that can increase the risk of developing severe Covid-19 infection? Several studies have shown that Galectins play a key role in the homeostasis of immune cells, and recently, a relationship was found between Covid-19 and Galectin-3 (Gal-3).It has been determined that an important area in the spike protein of Coronavirus-19 is almost exactly the same as the morphology of Gal-3, and these spike proteins are critical for the entry of the virus into host cells. We suspect that there is enough evidence to support a close relationship between PDs severity and Covid-19 infections. There is accumulating evidence to suggest a relationship between the severity of PD and the risk of infection with Covid-19, which requires further investigation. This relationship could be caused by Gal-3-mediated increased immune response and increased viral attachment. In this context, we want to emphasize the importance of keeping PD under control by maintaining rigorous oral hygiene during this troubled Covid-19 pandemic period. We would also like to point out the possibility that having PD may be a pre-disposition toward developing a severe Covid-19 infection.en_US
dc.language.isoengen_US
dc.publisherSAGE PUBLICATIONS LTD, 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLANDen_US
dc.relation.isversionof10.1177/1535370220953771en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCovid-19; Galectin-3; periodontal diseases; acute phase proteins; dentistry; oral hygieneen_US
dc.titleIs periodontal disease a risk factor for developing severe Covid-19 infection? The potential role of Galectin-3en_US
dc.typearticleen_US
dc.relation.journalEXPERIMENTAL BIOLOGY AND MEDICINEen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0001-5356-3665en_US
dc.contributor.authorID0000-0002-3803-7189en_US
dc.contributor.authorID0000-0002-4211-3359en_US
dc.contributor.authorID0000-0003-3681-6143en_US
dc.identifier.volume245en_US
dc.identifier.issue16en_US
dc.identifier.startpage1425en_US
dc.identifier.endpage1427en_US
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