Please use this identifier to cite or link to this item: http://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1663
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dc.contributor.authorAyhan, Eylem-
dc.contributor.authorAykan, Tuba-
dc.contributor.authorBernimoulin, Jean-Pierre-
dc.contributor.authorFriedmann, Anton-
dc.contributor.authorGokmenoglu, Ceren-
dc.contributor.authorKleber, Bernd-Michael-
dc.contributor.authorOzmeric, Nurdan-
dc.date.accessioned2022-08-16T05:57:07Z-
dc.date.available2022-08-16T05:57:07Z-
dc.date.issued2014-
dc.identifier.urihttp://doi.org/10.5114/ceji.2014.47737-
dc.identifier.urihttp://earsiv.odu.edu.tr:8080/xmlui/handle/11489/1663-
dc.description.abstractAim of the study: The present study investigated the hypothesis that upregulation of receptor activator of NF-kappaB ligand (RANKL) expression may be associated with upregulation of endothelial cell activitiy, which is common for periods of periodontal bone loss in chronic periodontitis. Material and methods: RANKL expression of activated cells in soft tissue biopsies with CD 31 activity and the presence of RANKL and osteoprotegerin (OPG) in gingival crevicular fluid (GCF) were assessed in chronic periodontitis patients. Biopsies from 17 patients and 10 healthy subjects were immunohistochemically analyzed. Clinical measurements [plaque index (PI), the gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL) and gingival bleeding index (GBI)] and GCF samples were obtained before and after periodontal therapy. Results: CD31 staining did not support the assumption that endothelium-like cells were predominantly associated with RANKL expression. Conclusions: RANKL-positive cells were widely distributed in periodontitis patients giving only partial support to the hypothesis that RANKL expression is restricted to T-and B-cell activation.en_US
dc.language.isoengen_US
dc.publisherTERMEDIA PUBLISHING HOUSE LTDKLEEBERGA ST 2, POZNAN 61-615, POLANDen_US
dc.relation.isversionof10.5114/ceji.2014.47737en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectgingival crevicular fluid, chronic periodontitis, immunohistochemistry, RANKL, CD31, osteoprotegerinen_US
dc.titleReceptor activator of NF-kappaB ligand (RANKL) and CD 31 expressions in chronic periodontitis patients before and after surgeryen_US
dc.typearticleen_US
dc.relation.journalCENTRAL EUROPEAN JOURNAL OF IMMUNOLOGYen_US
dc.contributor.departmentOrdu Üniversitesien_US
dc.contributor.authorID0000-0002-3803-7189en_US
dc.identifier.volume39en_US
dc.identifier.issue4en_US
dc.identifier.startpage508en_US
dc.identifier.endpage517en_US
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